Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.50 |
| ▸ | HPGD | P15428 | 7/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.50 |
| ▸ | POLB | P06746 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | BLM | P54132 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.50 |
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | PKM | P14618 | 3/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.50 |
| ▸ | RECQL | P46063 | 3/20 | 0.50 |
| ▸ | CASP1 | P29466 | 2/20 | 0.50 |
| ▸ | PTPN7 | P35236 | 2/20 | 0.50 |
| ▸ | CASP7 | P55210 | 2/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL577970 | 0.74 | KDM4E (0.56) | KDM4EALDH1A1HPGDHSD17B10TDP1 | |
| SCHEMBL2996550 | 0.72 | PDE10A (0.40) | KDM4EALDH1A1HPGDTDP1MAPT | |
| SCHEMBL382679 | 0.69 | RAB9A (0.47) | KDM4EALDH1A1HPGDHSD17B10TDP1 | |
| SCHEMBL6448031 | 0.69 | ALDH1A1 (0.43) | KDM4EALDH1A1HPGDHSD17B10TDP1 | |
| SCHEMBL3344845 | 0.69 | KDM4E (0.55) | KDM4EALDH1A1HPGDHSD17B10TDP1 | |
| SCHEMBL16720376 | 0.68 | NPC1 (0.50) | KDM4EALDH1A1HPGDHSD17B10POLB | |
| SCHEMBL1091953 | 0.68 | KDM4E (0.49) | KDM4EALDH1A1HPGDHSD17B10TDP1 | |
| SCHEMBL27734202 | 0.67 | MEN1 (1.00) | KDM4EALDH1A1HPGDHSD17B10TDP1 | |
| SCHEMBL529257 | 0.67 | ALDH1A1 (0.42) | KDM4EALDH1A1HPGDHSD17B10TDP1 | |
| SCHEMBL3422756 | 0.67 | CYP1A2 (0.54) | KDM4EALDH1A1HPGDHSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008103357-A1 | FUNGICIDAL TRICYCLIC 1,2,4-TRIAZOLES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-08-28 | — | — | WO | disclosed |