Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 9/20 | 0.43 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.42 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4786081 | 0.87 | MAPT (0.64) | MAPTHPGDRAB9AMAOBL3MBTL1 | |
| SCHEMBL26327986 | 0.85 | MAPT (0.68) | MAPTHPGDRAB9AMAOBL3MBTL1 | |
| SCHEMBL4744025 | 0.85 | MAPT (0.68) | MAPTHPGDRAB9AMAOBL3MBTL1 | |
| SCHEMBL4374328 | 0.81 | ESR1 (0.46) | MAPTHPGDCARM1PRMT6SMN1; SMN2 | |
| SCHEMBL9619575 | 0.80 | ESR1 (0.57) | MAPTHPGDRAB9AL3MBTL1SMN1; SMN2 | |
| SCHEMBL4543869 | 0.80 | ESR1 (0.57) | MAPTHPGDRAB9AL3MBTL1SMN1; SMN2 | |
| SCHEMBL4743133 | 0.78 | LMNA (0.47) | MAPTHPGDL3MBTL1SMN1; SMN2ALDH1A1 | |
| SCHEMBL1260786 | 0.78 | KMT2A (0.64) | MAPTHPGDRAB9AMAOBL3MBTL1 | |
| SCHEMBL10825749 | 0.78 | HPGD (0.56) | MAPTHPGDRAB9ACARM1PRMT6 | |
| SCHEMBL697644 | 0.77 | MAPT (0.56) | MAPTHPGDRAB9AMAOBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008099415-A1 | NOVEL SUBSTITUTED BIS-1, 2, 4-TRIOXANES AND A PROCESS FOR PREPARATION THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2008-08-21 | — | — | WO | disclosed |