Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | DAO | P14920 | 1/20 | 0.32 |
| ▸ | TYMP | P19971 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
| ▸ | PGK1 | P00558 | 1/20 | 0.31 |
| ▸ | PGK2 | P07205 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | SRC | P12931 | 1/20 | 0.30 |
| ▸ | ALDH1A2 | O94788 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27738318 | 0.84 | HTT (0.46) | HTTNPC1HPGDMAPK1RAB9A | |
| SCHEMBL4745127 | 0.83 | HTT (0.39) | HTTNPC1HPGDMAPK1RAB9A | |
| SCHEMBL27679482 | 0.78 | CYP19A1 (0.44) | HTTNPC1HPGDMAPK1RAB9A | |
| SCHEMBL200139 | 0.74 | HPGD (0.52) | HTTNPC1HPGDMAPK1RAB9A | |
| SCHEMBL1091644 | 0.73 | HTT (0.35) | HTTNPC1HPGDMAPK1RAB9A | |
| SCHEMBL2697153 | 0.71 | HTT (0.37) | HTTNPC1HPGDMAPK1RAB9A | |
| SCHEMBL18602121 | 0.69 | HTT (0.38) | HTTNPC1HPGDMAPK1RAB9A | |
| SCHEMBL10430962 | 0.67 | SKP2 (0.48) | HTTNPC1HPGDMAPK1RAB9A | |
| SCHEMBL8732546 | 0.67 | CCR5 (0.45) | SKP2CYP19A1THRBSRC | |
| SCHEMBL28260132 | 0.67 | GABRA1 (0.40) | HTTNPC1HPGDMAPK1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012118233-A1 | ADDITION POLYMERIZATION METHOD, PREPOLYMERIZED CATALYTIC COMPONENT FOR ADDITION POLYMERIZATION, AND METHOD FOR PRODUCING ADDITION POLYMER | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-09-07 | — | — | WO | disclosed |
| WO-2008105546-A1 | PRODUCTION PROCESS OF OLEFIN POLYMER | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2008-09-04 | — | — | WO | disclosed |