SCHEMBL27679482

SCHEMBL27679482

CCCCCc1c(C)c(C)cc(C)c1C

nearest known ligand 0.44

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 1/20 0.44
PTGS2 P35354 3/20 0.41
CYP3A4 P08684 1/20 0.41
NPC1 O15118 1/20 0.40
HPGD P15428 1/20 0.40
MAPK1 P28482 1/20 0.40
HTT P42858 1/20 0.40
RAB9A P51151 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
ALOX5 P09917 5/20 0.39
CCR5 P51681 2/20 0.39
TYR P14679 1/20 0.38
THRB P10828 1/20 0.37
SRC P12931 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27738318 0.92 HTT (0.46) CYP19A1PTGS2CYP3A4NPC1HPGD
SCHEMBL8732546 0.83 CCR5 (0.45) CYP19A1PTGS2CYP3A4ALOX5CCR5
SCHEMBL5800572 0.81 CYP19A1 (0.46) CYP19A1PTGS2CYP3A4NPC1HPGD
SCHEMBL5678432 0.79 ALOX5 (0.56) CYP19A1PTGS2CYP3A4NPC1HPGD
SCHEMBL1613192 0.78 PGK1 (0.30)
SCHEMBL4743744 0.78 HTT (0.39) CYP19A1NPC1HPGDMAPK1HTT
SCHEMBL1083389 0.78 SKP2 (0.41) CYP19A1PTGS2ALOX5CCR5TYR
SCHEMBL18371585 0.76 CYP19A1 (0.55) CYP19A1PTGS2CYP3A4NPC1HPGD
SCHEMBL29487433 0.76 TYR (0.44) PTGS2CYP3A4HTTTYRSRC
SCHEMBL1610978 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100509162-C Process for preparing a catalyst for partial oxidation of toluene LG CHEMICAL LTD (KR) 2009-07-08 CN disclosed
CN-101018607-A Method for preparing catalyst for partial oxidation of methylbenzenes LG CHEMICAL LTD (KR) 2007-08-15 CN disclosed