Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 5/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.46 |
| ▸ | FDPS | P14324 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16974745 | 0.82 | SMN1; SMN2 (0.52) | NPSR1SMN1; SMN2LMNAMAPK1POLB | |
| SCHEMBL25752781 | 0.79 | SMN1; SMN2 (0.59) | SMN1; SMN2LMNAMAPK1POLBTSHR | |
| SCHEMBL5366533 | 0.78 | FDPS (0.59) | NPSR1SMN1; SMN2LMNAPOLBTSHR | |
| SCHEMBL1893010 | 0.78 | NPSR1 (1.00) | NPSR1LMNAPOLBKDM4E | |
| Ammonia Solution, Strong SCHEMBL9173134 | 0.77 | NPSR1 (0.96) | NPSR1LMNAPOLBKDM4E | |
| SCHEMBL24052074 | 0.73 | LMNA (0.55) | SMN1; SMN2LMNAMAPK1POLBNPC1 | |
| SCHEMBL4743946 | 0.73 | FDPS (0.61) | SMN1; SMN2LMNAMAPK1POLBNPC1 | |
| SCHEMBL1243824 | 0.72 | KCNA5 (0.47) | NPC1RAB9AMAPTPKM | |
| SCHEMBL31482560 | 0.72 | KCNA5 (0.47) | NPC1RAB9AMAPTPKM | |
| SCHEMBL10885930 | 0.72 | NPSR1 (0.86) | NPSR1LMNAMAPK1TSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008113161-A1 | PHOSPHATE PRODRUGS OF QUINAZOLINYL NITROFURANS, METHODS OF OBTAINING, AND USE OF SAME | ULYSSES PHARMACEUTICAL PRODUCTS INC. (CA) | 2008-09-25 | — | — | WO | disclosed |