Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | CFTR | P13569 | 1/20 | 0.43 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
| ▸ | ALPL | P05186 | 4/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7793582 | 0.81 | KDM4E (0.43) | FDPSPOLBMAPTLMNANPSR1 | |
| SCHEMBL8159782 | 0.81 | FDPS (0.60) | FDPSPOLBNPC1RAB9ACFTR | |
| SCHEMBL4743968 | 0.78 | NPSR1 (0.64) | FDPSPOLBTSHRNPC1RAB9A | |
| SCHEMBL5367565 | 0.77 | KMT2A (0.50) | FDPSPOLBTSHRPKMALDH1A1 | |
| SCHEMBL7793634 | 0.75 | FDFT1 (0.42) | POLBMAPTLMNA | |
| SCHEMBL7793613 | 0.75 | L3MBTL1 (0.45) | POLBMAPTALDH1A1LMNA | |
| SCHEMBL21501951 | 0.75 | FDPS (0.39) | FDPSPOLBSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL8166203 | 0.75 | FDPS (0.69) | FDPSPOLBNPC1RAB9ACFTR | |
| SCHEMBL5359859 | 0.75 | TSHR (0.42) | FDPSPOLBTSHRNPC1RAB9A | |
| SCHEMBL8159300 | 0.74 | FDPS (1.00) | FDPSCFTRGOPCLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7208481-B2 | Aminodiphosphonate apolipoprotein E modulators | ILEX PRODUCTS, INC. (US) | 2007-04-24 | — | — | US | claimed |
| US-20050075317-A1 | Aminodiphosphonate apolipoprotein e modulators | PHAN HIEU TRUNG (CH) | 2005-04-07 | — | — | US | claimed |
| EP-1482897-A2 | AMINODIPHOSPHONATE APOLIPOPROTEIN E MODULATORS | Ilex Products, Inc. (US) | 2004-12-08 | — | — | EP | claimed |
| WO-2003070169-A2 | AMINODIPHOSPHONATE APOLIPOPROTEIN E MODULATORS | ILEX PRODUCTS, INC. (US) | 2003-08-28 | — | — | WO | claimed |
| US-7208481-B2 | Aminodiphosphonate apolipoprotein E modulators | ILEX PRODUCTS, INC. (US) | 2007-04-24 | — | — | US | disclosed |
| US-20050075317-A1 | Aminodiphosphonate apolipoprotein e modulators | PHAN HIEU TRUNG (CH) | 2005-04-07 | — | — | US | disclosed |
| EP-1482897-A2 | AMINODIPHOSPHONATE APOLIPOPROTEIN E MODULATORS | Ilex Products, Inc. (US) | 2004-12-08 | — | — | EP | disclosed |
| WO-2003070169-A2 | AMINODIPHOSPHONATE APOLIPOPROTEIN E MODULATORS | ILEX PRODUCTS, INC. (US) | 2003-08-28 | — | — | WO | disclosed |
| EP-0563107-B1 | NOVEL METHYLENEBISPHOSPHONIC ACID DERIVATIVES | LEIRAS OY (FI) | 2000-05-03 | — | — | EP | disclosed |
| US-5393748-A | Treating bone disorders, Paget* s disease, calcium metabolism disorders | LEIRAS OY (FI) | 1995-02-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050075317-A1 | Aminodiphosphonate apolipoprotein e modulators | APOB, APOL1, NAPEPLD | FDPS 526/4885POLB 2745/4885TSHR 4299/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.