Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.55 |
| ▸ | CA1 | P00915 | 2/20 | 0.55 |
| ▸ | CA2 | P00918 | 2/20 | 0.55 |
| ▸ | CA9 | Q16790 | 2/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | CTSL | P07711 | 1/20 | 0.50 |
| ▸ | CTSS | P25774 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CTSK | P43235 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | ELANE | P08246 | 1/20 | 0.48 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20299925 | 0.85 | CA12 (0.52) | CA12CA1CA2CA9ATM | |
| SCHEMBL6703437 | 0.82 | CTSK (0.54) | CA12CA1CA2CA9CTSL | |
| SCHEMBL1947879 | 0.82 | ALDH1A1 (0.65) | CA12CA1CA2CA9NPC1 | |
| SCHEMBL1287193 | 0.82 | CA12 (0.52) | CA12CA1CA2CA9ATM | |
| SCHEMBL11100708 | 0.82 | CA12 (0.63) | CA12CA1CA2CA9NPC1 | |
| SCHEMBL201855 | 0.81 | ALDH1A1 (0.62) | ATMNPC1RAB9ACTSLCTSS | |
| SCHEMBL1107604 | 0.81 | ALDH1A1 (0.62) | ATMNPC1RAB9ACTSLCTSS | |
| SCHEMBL320610 | 0.81 | ALDH1A1 (0.62) | ATMNPC1RAB9ACTSLCTSS | |
| SCHEMBL27577606 | 0.81 | SIRT2 (0.51) | CA12CA1CA2CA9CTSL | |
| SCHEMBL4756378 | 0.81 | CA12 (0.58) | CA12CA1CA2CA9NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008098396-A2 | OXAZOLIDINONES AND THEIR USE AS HYPOCHOLESTEROLEMIC AGENTS | LIPIDEON BIOTECHNOLOGY AG (CH) | 2008-08-21 | — | — | WO | disclosed |