Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 8/20 | 0.56 |
| ▸ | PPARG | P37231 | 5/20 | 0.56 |
| ▸ | MAOA | P21397 | 7/20 | 0.46 |
| ▸ | MAOB | P27338 | 7/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9178901 | 0.88 | MAOA (0.58) | PPARAPPARGMAOAMAOBNPC1 | |
| SCHEMBL9261947 | 0.87 | PPARG (0.49) | PPARAPPARGFFAR1 | |
| SCHEMBL4748219 | 0.87 | MAOA (0.56) | PPARAPPARGMAOAMAOBNPC1 | |
| SCHEMBL4744035 | 0.82 | PPARA (0.65) | PPARAPPARGFFAR1 | |
| SCHEMBL4748241 | 0.82 | PPARA (0.62) | PPARAPPARGFFAR1 | |
| SCHEMBL8545784 | 0.79 | PPARG (0.55) | PPARAPPARG | |
| SCHEMBL9092427 | 0.78 | PPARG (0.45) | PPARAPPARGFFAR1 | |
| SCHEMBL17894399 | 0.76 | MAOB (0.72) | MAOAMAOBNPC1RAB9A | |
| SCHEMBL4744208 | 0.76 | PPARG (0.59) | PPARAPPARGFFAR1 | |
| SCHEMBL7152950 | 0.76 | PPARA (0.50) | PPARAPPARGMAOAMAOBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008117982-A1 | HETEROCYCLIC CARBOXYLIC ACID DERIVATIVES AND PHARMACEUTICAL COMPOSITION FOR INHIBITING LIPID ACCUMULATION CONTAINING SAME | CRYSTAL GENOMICS, INC. (KR) | 2008-10-02 | — | — | WO | disclosed |