Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 13/20 | 0.62 |
| ▸ | KDR | P35968 | 1/20 | 0.61 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.58 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.55 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.55 |
| ▸ | PPARG | P37231 | 9/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4746564 | 0.89 | PPARA (0.64) | PPARAKDRFFAR1GPBAR1CYSLTR1 | |
| SCHEMBL4748568 | 0.88 | KDR (0.53) | PPARAKDRFFAR1GPBAR1CYSLTR1 | |
| SCHEMBL4744758 | 0.88 | PPARA (0.59) | PPARAKDRFFAR1PPARGDRD2 | |
| SCHEMBL4744035 | 0.86 | PPARA (0.65) | PPARAKDRFFAR1GPBAR1CYSLTR1 | |
| SCHEMBL4747041 | 0.86 | FFAR1 (0.72) | PPARAKDRFFAR1CYSLTR1PPARG | |
| SCHEMBL27321832 | 0.80 | KDR (0.53) | PPARAKDRFFAR1GPBAR1CYSLTR1 | |
| SCHEMBL4748219 | 0.79 | MAOA (0.56) | PPARAFFAR1PPARG | |
| SCHEMBL27921625 | 0.78 | PPARA (0.57) | PPARAFFAR1GPBAR1CYSLTR1PPARG | |
| SCHEMBL5761027 | 0.78 | PPARA (0.49) | PPARAFFAR1PPARGTSHRSMN1; SMN2 | |
| SCHEMBL9173551 | 0.77 | PPARA (0.62) | PPARAFFAR1PPARGTSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008117982-A1 | HETEROCYCLIC CARBOXYLIC ACID DERIVATIVES AND PHARMACEUTICAL COMPOSITION FOR INHIBITING LIPID ACCUMULATION CONTAINING SAME | CRYSTAL GENOMICS, INC. (KR) | 2008-10-02 | — | — | WO | disclosed |