Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.66 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.63 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.49 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | MPO | P05164 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 3/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4932707 | 0.82 | MAOA (0.95) | MAOACHRM2SIGMAR1MEN1KMT2A | |
| SCHEMBL4642587 | 0.80 | MAOA (1.00) | MAOACHRM2SIGMAR1MEN1KMT2A | |
| SCHEMBL7202099 | 0.80 | MAOA (1.00) | MAOACHRM2SIGMAR1MEN1KMT2A | |
| SCHEMBL8851048 | 0.80 | MAOA (1.00) | MAOACHRM2SIGMAR1MEN1KMT2A | |
| SCHEMBL16260102 | 0.80 | MAOA (1.00) | MAOACHRM2SIGMAR1MEN1KMT2A | |
| SCHEMBL8644839 | 0.80 | MAOA (1.00) | MAOACHRM2SIGMAR1MEN1KMT2A | |
| SCHEMBL29361832 | 0.80 | MAOA (1.00) | MAOACHRM2SIGMAR1MEN1KMT2A | |
| SCHEMBL8024796 | 0.78 | CHRM2 (0.91) | MAOACHRM2SIGMAR1MEN1KMT2A | |
| SCHEMBL8021930 | 0.78 | CHRM2 (1.00) | MAOACHRM2SIGMAR1MEN1KMT2A | |
| SCHEMBL8021157 | 0.78 | CHRM2 (1.00) | MAOACHRM2SIGMAR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008112251-A1 | CYCLOPROPYL-CONTAINING POLYAMINE ANALOGS AS DISEASE THERAPIES | PROGEN PHARMACEUTICALS, INC. (US) | 2008-09-18 | — | — | WO | disclosed |