Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1G | O43497 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4748785 | 0.98 | CACNA1G (0.43) | CACNA1GKDM4EALDH1A1GAAFAAH | |
| SCHEMBL4744647 | 0.93 | KDM4E (0.40) | CACNA1GKDM4EALDH1A1GAAOPRL1 | |
| SCHEMBL4744995 | 0.92 | MEN1 (0.41) | CACNA1GKDM4EALDH1A1GAAOPRL1 | |
| SCHEMBL4802218 | 0.92 | KDM4E (0.40) | CACNA1GKDM4EALDH1A1GAAOPRL1 | |
| SCHEMBL4747027 | 0.91 | ALDH1A1 (0.40) | CACNA1GKDM4EALDH1A1GAAOPRL1 | |
| SCHEMBL4748756 | 0.91 | MEN1 (0.47) | CACNA1GKDM4EALDH1A1GAAOPRL1 | |
| SCHEMBL4747842 | 0.91 | CACNA1G (0.43) | CACNA1GKDM4EALDH1A1GAAOPRL1 | |
| SCHEMBL4748172 | 0.91 | ALDH1A1 (0.42) | CACNA1GKDM4EALDH1A1GAAOPRL1 | |
| SCHEMBL4744963 | 0.91 | KDM4E (0.40) | CACNA1GKDM4EALDH1A1GAAOPRL1 | |
| SCHEMBL4744841 | 0.90 | MEN1 (0.39) | CACNA1GKDM4EALDH1A1GAAOPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008117148-A1 | SUBSTITUTED OXADIAZOLE ANALOGS AS CALCIUM CHANNEL ANTAGONISTS | PFIZER PRODUCTS INC. (US) | 2008-10-02 | — | — | WO | claimed |
| WO-2008117148-A1 | SUBSTITUTED OXADIAZOLE ANALOGS AS CALCIUM CHANNEL ANTAGONISTS | PFIZER PRODUCTS INC. (US) | 2008-10-02 | — | — | WO | disclosed |