Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | RBP1 | P09455 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | PHGDH | O43175 | 1/20 | 0.40 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4913486 | 0.97 | MEN1 (0.43) | MEN1KMT2AHTTALDH1A1MAPT | |
| SCHEMBL4748785 | 0.93 | CACNA1G (0.43) | MEN1KMT2AHTTALDH1A1LMNA | |
| SCHEMBL4747027 | 0.92 | ALDH1A1 (0.40) | MEN1KMT2AHTTALDH1A1LMNA | |
| SCHEMBL4747811 | 0.92 | CACNA1G (0.43) | MEN1KMT2AHTTALDH1A1LMNA | |
| SCHEMBL4748172 | 0.92 | ALDH1A1 (0.42) | MEN1KMT2AHTTALDH1A1LMNA | |
| SCHEMBL4744995 | 0.92 | MEN1 (0.41) | MEN1KMT2AHTTALDH1A1KDM4E | |
| SCHEMBL4744345 | 0.91 | CACNA1G (0.43) | MEN1KMT2AHTTALDH1A1LMNA | |
| SCHEMBL4744841 | 0.91 | MEN1 (0.39) | MEN1KMT2AHTTALDH1A1LMNA | |
| SCHEMBL4744647 | 0.91 | KDM4E (0.40) | MEN1KMT2AHTTALDH1A1LMNA | |
| SCHEMBL4747842 | 0.90 | CACNA1G (0.43) | MEN1KMT2AHTTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008117148-A1 | SUBSTITUTED OXADIAZOLE ANALOGS AS CALCIUM CHANNEL ANTAGONISTS | PFIZER PRODUCTS INC. (US) | 2008-10-02 | — | — | WO | claimed |