Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.61 |
| ▸ | POLB | P06746 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 5/20 | 0.37 |
| ▸ | RAB9A | P51151 | 5/20 | 0.37 |
| ▸ | HTT | P42858 | 5/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | GALR3 | O60755 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | RAD52 | P43351 | 1/20 | 0.37 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL996895 | 0.92 | ALDH1A1 (0.63) | TLR8POLBALDH1A1KMT2AHTT | |
| SCHEMBL998200 | 0.84 | — | — | |
| SCHEMBL2328687 | 0.79 | ALDH1A1 (0.85) | TLR8POLBALDH1A1KMT2ATBXAS1 | |
| SCHEMBL5287541 | 0.79 | ALDH1A1 (0.85) | TLR8POLBALDH1A1KMT2ATBXAS1 | |
| SCHEMBL363481 | 0.79 | ALDH1A1 (0.85) | TLR8POLBALDH1A1KMT2ATBXAS1 | |
| SCHEMBL25267373 | 0.79 | ALDH1A1 (0.85) | TLR8POLBALDH1A1KMT2ATBXAS1 | |
| SCHEMBL25240227 | 0.79 | ALDH1A1 (0.85) | TLR8POLBALDH1A1KMT2ATBXAS1 | |
| SCHEMBL25270261 | 0.79 | ALDH1A1 (0.85) | TLR8POLBALDH1A1KMT2ATBXAS1 | |
| SCHEMBL25267924 | 0.79 | ALDH1A1 (0.85) | TLR8POLBALDH1A1KMT2ATBXAS1 | |
| SCHEMBL1137200 | 0.79 | ALDH1A1 (0.85) | TLR8POLBALDH1A1KMT2ATBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2112206-B1 | Polymer Composition | ROHM & HAAS (US) | 2016-06-29 | — | — | EP | disclosed |
| EP-2166043-B1 | Thickener composition and method for thickening aqueous systems | ROHM & HAAS (US) | 2016-04-27 | — | — | EP | disclosed |
| EP-2166044-B1 | Thickened compositions and method for thickening aqueous polymer compositions | ROHM & HAAS (US) | 2012-02-01 | — | — | EP | disclosed |
| US-20110281980-A1 | Thickener composition and method for thickening aqueous systems | BOBSEIN BARRETT RICHARD (US) | 2011-11-17 | — | — | US | disclosed |
| US-8034869-B2 | Thickened compositions and method for thickening aqueous polymer compositions | ROHM AND HAAS COMPANY (US) | 2011-10-11 | — | — | US | disclosed |
| US-7985795-B2 | Thickener composition and method for thickening aqueous systems | ROHM AND HAAS COMPANY (US) | 2011-07-26 | — | — | US | disclosed |
| EP-1972665-B1 | Thickener composition and method for thickening aqueous systems | ROHM & HAAS (US) | 2011-04-27 | — | — | EP | disclosed |
| US-20100286434-A1 | Ethylenically unsaturated monomers for thickener compositions | BOBSEIN BARRETT RICHARD | 2010-11-11 | — | — | US | disclosed |
| US-20100261813-A1 | Thickener composition and method for thickening aqueous systems | BOBSEIN BARRETT RICHARD | 2010-10-14 | — | — | US | disclosed |
| US-20100227953-A1 | Thickened compositions and method for thickening aqueous polymer compositions | ROHM AND HAAS COMPANY | 2010-09-09 | — | — | US | disclosed |
| US-7741402-B2 | Thickener composition and method for thickening aqueous systems | ROHM AND HAAS COMPANY (US) | 2010-06-22 | — | — | US | disclosed |
| US-20100076145-A1 | Thickener composition and method for thickening aqueous systems | ROHM AND HAAS COMPANY | 2010-03-25 | — | — | US | disclosed |
| EP-2166044-A1 | Thickened compositions and method for thickening aqueous polymer compositions | Rohm and Haas Company (US) | 2010-03-24 | — | — | EP | disclosed |
| EP-2166043-A2 | Thickener composition and method for thickening aqueous systems | Rohm and Haas Company (US) | 2010-03-24 | — | — | EP | disclosed |
| EP-2112206-A1 | Polymer Composition | Rohm and Haas Company (US) | 2009-10-28 | — | — | EP | disclosed |
| US-20080234411-A1 | Thickener composition and method for thickening aqueous systems | ROHM AND HAAS COMPANY | 2008-09-25 | — | — | US | disclosed |
| EP-1972665-A2 | Thickener composition and method for thickening aqueous systems | Rohm and Haas Company (US) | 2008-09-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100286434-A1 | Ethylenically unsaturated monomers for thickener compositions | ELOVL1, ELOVL6, ELOVL5 | TLR8 3233/4885POLB 802/4885ALDH1A1 2760/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.