Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | PPARG | P37231 | 7/20 | 0.49 |
| ▸ | PPARA | Q07869 | 6/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | PPARD | Q03181 | 3/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.45 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4788139 | 1.00 | ALDH1A1 (0.51) | ALDH1A1KDM4EPPARGPPARAKMT2A | |
| SCHEMBL4744558 | 1.00 | ALDH1A1 (0.51) | ALDH1A1KDM4EPPARGPPARAKMT2A | |
| SCHEMBL4747043 | 0.95 | PPARG (0.50) | ALDH1A1KDM4EPPARGPPARAPPARD | |
| SCHEMBL4747044 | 0.95 | PPARG (0.50) | ALDH1A1KDM4EPPARGPPARAPPARD | |
| SCHEMBL4788193 | 0.93 | PPARG (0.52) | ALDH1A1KDM4EPPARGPPARAPPARD | |
| SCHEMBL4788199 | 0.93 | PPARG (0.52) | ALDH1A1KDM4EPPARGPPARAPPARD | |
| SCHEMBL4746574 | 0.92 | ALDH1A1 (0.49) | ALDH1A1KDM4EPPARGPPARAKMT2A | |
| SCHEMBL4748235 | 0.92 | ALDH1A1 (0.49) | ALDH1A1KDM4EPPARGPPARAKMT2A | |
| SCHEMBL4748026 | 0.92 | ALDH1A1 (0.49) | ALDH1A1KDM4EPPARGPPARAKMT2A | |
| SCHEMBL4748101 | 0.91 | PPARG (0.53) | ALDH1A1KDM4EPPARGPPARAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008117982-A1 | HETEROCYCLIC CARBOXYLIC ACID DERIVATIVES AND PHARMACEUTICAL COMPOSITION FOR INHIBITING LIPID ACCUMULATION CONTAINING SAME | CRYSTAL GENOMICS, INC. (KR) | 2008-10-02 | — | — | WO | disclosed |