Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | PPARG | P37231 | 6/20 | 0.52 |
| ▸ | PPARA | Q07869 | 6/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4744723 | 0.93 | PPARG (0.52) | ALDH1A1SMN1; SMN2POLBKDM4EMEN1 | |
| SCHEMBL4744720 | 0.93 | PPARG (0.52) | ALDH1A1SMN1; SMN2POLBKDM4EMEN1 | |
| SCHEMBL4744476 | 0.92 | PPARG (0.55) | ALDH1A1SMN1; SMN2POLBPPARGPPARA | |
| SCHEMBL4744118 | 0.92 | PPARG (0.55) | ALDH1A1SMN1; SMN2POLBPPARGPPARA | |
| SCHEMBL4743930 | 0.91 | PPARG (0.53) | ALDH1A1SMN1; SMN2POLBKDM4EMEN1 | |
| SCHEMBL4743922 | 0.91 | PPARG (0.53) | ALDH1A1SMN1; SMN2POLBKDM4EMEN1 | |
| SCHEMBL4748208 | 0.91 | PPARG (0.53) | ALDH1A1SMN1; SMN2POLBKDM4EMEN1 | |
| SCHEMBL4744641 | 0.90 | PPARG (0.56) | ALDH1A1POLBMEN1KMT2APPARG | |
| SCHEMBL4748381 | 0.90 | PPARG (0.56) | ALDH1A1POLBMEN1KMT2APPARG | |
| SCHEMBL4746251 | 0.90 | PPARG (0.56) | ALDH1A1POLBMEN1KMT2APPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008117982-A1 | HETEROCYCLIC CARBOXYLIC ACID DERIVATIVES AND PHARMACEUTICAL COMPOSITION FOR INHIBITING LIPID ACCUMULATION CONTAINING SAME | CRYSTAL GENOMICS, INC. (KR) | 2008-10-02 | — | — | WO | disclosed |