⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7164426 | 0.85 | ALDH1A1 (0.32) | — | |
| SCHEMBL6967790 | 0.84 | CHRM2 (0.33) | — | |
| SCHEMBL6974356 | 0.82 | CHRM2 (0.42) | — | |
| SCHEMBL12790551 | 0.82 | FDPS (0.33) | — | |
| SCHEMBL13763694 | 0.81 | FDPS (0.34) | — | |
| SCHEMBL1464011 | 0.81 | — | — | |
| SCHEMBL18599612 | 0.79 | — | — | |
| SCHEMBL20381190 | 0.79 | — | — | |
| SCHEMBL20851501 | 0.79 | — | — | |
| SCHEMBL1105149 | 0.77 | DNM1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220389191-A1 | POLYMER COMPOSITION COMPRISING PHOSPHONATE FLAME RETARDANT | CHEMISCHE FABRIK BUDENHEIM KG (DE) | 2022-12-08 | — | — | US | disclosed |
| WO-2021237112-A1 | NOTCH INHIBITORS AND USES THEREOF | STEMSYNERGY THERAPEUTICS, INC. (US) | 2021-11-25 | — | — | WO | disclosed |
| WO-2021237111-A1 | NOTCH INHIBITORS AND USES THEREOF | STEMSYNERGY THERAPEUTICS, INC. (US) | 2021-11-25 | — | — | WO | disclosed |
| US-10982124-B2 | Drill-in fluid compositions and methods | SAUDI ARABIAN OIL COMPANY (SA) | 2021-04-20 | — | — | US | disclosed |
| US-10308754-B2 | Composition | HUNTSMAN PETROCHEMICAL LLC (US) | 2019-06-04 | — | — | US | disclosed |
| US-20190136110-A1 | DRILL-IN FLUID COMPOSITIONS AND METHODS | SAUDI ARABIAN OIL COMPANY (SA) | 2019-05-09 | — | — | US | disclosed |
| US-8324257-B2 | Mitotic kinesin inhibitors and methods of use thereof | ARRAY BIOPHARMA INC. (US) | 2012-12-04 | — | — | US | disclosed |
| US-20120225886-A1 | NOVEL PYRROLIDINE DERIVED BETA 3 ADRENERGIC RECEPTOR AGONISTS | MERCK SHARP & DOHME, CORP. (US) | 2012-09-06 | — | — | US | disclosed |
| US-20100130469-A1 | 2, 6-NAPHTHRIDINE DERIVATIVES | VAN EIS MAURICE | 2010-05-27 | — | — | US | disclosed |
| US-20100104659-A1 | BENZOPYRANOPYRAZOLES | 4SC AG (DE) | 2010-04-29 | — | — | US | disclosed |
| US-20100041719-A1 | MITOTIC KINESIN INHIBITORS AND METHODS OF USE THEREOF | ARRAY BIOPHARMA INC. (US) | 2010-02-18 | — | — | US | disclosed |
| US-20090247519-A1 | AMINO-ETHYL-AMINO-ARYL (AEAA) COMPOUNDS AND THEIR USE | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2009-10-01 | — | — | US | disclosed |
| WO-2008100772-A1 | CHAIN EXTENDERS | ALBEMARLE CORPORATION (US) | 2008-08-21 | — | — | WO | disclosed |
| US-7179816-B2 | Chemical derivatives and their application as antitelomerase agents | AVENTIS PHARMA S.A. (FR) | 2007-02-20 | — | — | US | disclosed |