Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 15/20 | 0.59 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.55 |
| ▸ | PPARG | P37231 | 10/20 | 0.53 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | DRD4 | P21917 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4747894 | 0.88 | PPARA (0.62) | PPARAFFAR1PPARGDRD2DRD4 | |
| SCHEMBL4748241 | 0.86 | PPARA (0.62) | PPARAFFAR1PPARG | |
| SCHEMBL4744857 | 0.86 | FFAR1 (0.68) | PPARAFFAR1PPARGDRD2DRD4 | |
| SCHEMBL5761027 | 0.85 | PPARA (0.49) | PPARAFFAR1PPARGDRD2DRD4 | |
| SCHEMBL4748219 | 0.79 | MAOA (0.56) | PPARAFFAR1PPARG | |
| SCHEMBL5400326 | 0.78 | FFAR1 (0.55) | PPARAFFAR1PPARGDRD2DRD4 | |
| SCHEMBL4746564 | 0.77 | PPARA (0.64) | PPARAFFAR1PPARGKDR | |
| SCHEMBL5761300 | 0.76 | PPARA (0.51) | PPARAFFAR1PPARG | |
| SCHEMBL7156371 | 0.76 | PPARA (0.50) | PPARAFFAR1PPARGDRD2DRD4 | |
| SCHEMBL4033640 | 0.76 | KDR (0.79) | PPARAFFAR1PPARGKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008117982-A1 | HETEROCYCLIC CARBOXYLIC ACID DERIVATIVES AND PHARMACEUTICAL COMPOSITION FOR INHIBITING LIPID ACCUMULATION CONTAINING SAME | CRYSTAL GENOMICS, INC. (KR) | 2008-10-02 | — | — | WO | disclosed |