SCHEMBL4744924

SCHEMBL4744924

CC(O)Oc1ccccc1-c1ccccc1OC(C)O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRA2A P08913 8/20 0.41
ADRA2B P18089 8/20 0.41
ADRA2C P18825 8/20 0.41
IRAK4 Q9NWZ3 1/20 0.38
KMT2A Q03164 1/20 0.38
CA1 P00915 2/20 0.37
CA2 P00918 2/20 0.37
CA7 P43166 2/20 0.37
CA9 Q16790 2/20 0.37
ADRB2 P07550 1/20 0.37
ALDH1A1 P00352 1/20 0.36
ACHE P22303 1/20 0.36
CA12 O43570 1/20 0.36
CA4 P22748 1/20 0.36
CA14 Q9ULX7 1/20 0.36
MAOA P21397 3/20 0.36
MAOB P27338 3/20 0.36
AKR1C3 P42330 1/20 0.36
AKR1C2 P52895 1/20 0.36
NISCH Q9Y2I1 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2962387 0.87 KMT2A (0.47) IRAK4KMT2ACA1CA2CA7
SCHEMBL11012886 0.87 KMT2A (0.47) IRAK4KMT2ACA1CA2CA7
SCHEMBL159004 0.87 ADRA2A (0.50) ADRA2AADRA2BADRA2CKMT2AADRB2
SCHEMBL28120543 0.85 ALDH1A1 (0.40) ADRA2AADRA2BADRA2CKMT2AADRB2
SCHEMBL3632568 0.80 IRAK4 (0.50) ADRA2AADRA2BADRA2CIRAK4KMT2A
SCHEMBL31634047 0.80 IRAK4 (0.50) ADRA2AADRA2BADRA2CIRAK4KMT2A
SCHEMBL2352949 0.79 CA2 (0.54) ADRA2AADRA2BADRA2CIRAK4KMT2A
SCHEMBL516163 0.79 KMT2A (0.60) ADRA2AADRA2BADRA2CKMT2ACA1
SCHEMBL515976 0.79 CYP1A2 (0.48) ADRA2BKMT2AADRB2ALDH1A1NISCH
SCHEMBL5752973 0.78 ADRA2A (0.60) ADRA2AADRA2BADRA2CALDH1A1MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9164195-B2 Methods of making microstructured optical films comprising biphenyl difunctional monomers 3M INNOVATIVE PROPERTIES COMPANY (US) 2015-10-20 US disclosed
US-20130149495-A1 METHODS OF MAKING MICROSTRUCTURED OPTICAL FILMS COMPRISING BIPHENYL DIFUNCTIONAL MONOMERS 3M INNOVATIVE PROPERTIES COMPANY (US) 2013-06-13 US disclosed
WO-2008112451-A2 MICROSTRUCTURED OPTICAL FILMS COMPRISING BIPHENYL DIFUNCTIONAL MONOMERS 3M INNOVATIVE PROPERTIES COMPANY (US) 2008-09-18 WO disclosed
US-20080221291-A1 MICROSTRUCTURED OPTICAL FILMS COMPRISING BIPHENYL DIFUNCTIONAL MONOMERS 3M INNOVATIVE PROPERTIES COMPANY 2008-09-11 US disclosed
US-3952063-A Process for the preparation of an organomercaptophenol from sulfur, a phenol, and an activated olefin or an epoxy compound GENERAL ELECTRIC COMPANY (US) 1976-04-20 US disclosed