Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 4/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.48 |
| ▸ | PDE4A | P27815 | 1/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.46 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | LTA4H | P09960 | 3/20 | 0.45 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14068463 | 1.00 | FFAR1 (0.52) | FFAR1NPC1RAB9ASMN1; SMN2FFAR4 | |
| SCHEMBL14068528 | 0.94 | RAB9A (0.51) | FFAR1NPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL4744523 | 0.94 | RAB9A (0.51) | FFAR1NPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL4742525 | 0.90 | MEN1 (0.49) | FFAR1NPC1RAB9ASMN1; SMN2FFAR4 | |
| SCHEMBL14068292 | 0.81 | CXCL12 (0.47) | FFAR1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL4745611 | 0.78 | MEN1 (0.52) | FFAR1NPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL14068553 | 0.78 | MEN1 (0.52) | FFAR1NPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL14104633 | 0.72 | NPY5R (0.44) | FFAR1NPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL8010842 | 0.72 | FFAR1 (0.70) | FFAR1FFAR4LTA4H | |
| SCHEMBL1747136 | 0.70 | FFAR1 (0.72) | FFAR1NPC1RAB9ASMN1; SMN2FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008104875-A1 | OXAZOLIDINONES AS CHOLESTEROL ABSORPTION INHIBITORS | PFIZER PRODUCTS INC. (US) | 2008-09-04 | — | — | WO | disclosed |