Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 7/20 | 0.48 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | AR | P10275 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | GPR34 | Q9UPC5 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14068463 | 0.90 | FFAR1 (0.52) | MEN1KMT2AALDH1A1FFAR1FFAR4 | |
| SCHEMBL4745114 | 0.90 | FFAR1 (0.52) | MEN1KMT2AALDH1A1FFAR1FFAR4 | |
| SCHEMBL14068292 | 0.89 | CXCL12 (0.47) | MEN1KMT2AFFAR1LMNAGAA | |
| SCHEMBL4745611 | 0.86 | MEN1 (0.52) | MEN1KMT2AALDH1A1RECQLFFAR1 | |
| SCHEMBL14068553 | 0.86 | MEN1 (0.52) | MEN1KMT2AALDH1A1RECQLFFAR1 | |
| SCHEMBL4744523 | 0.82 | RAB9A (0.51) | MEN1KMT2AALDH1A1FFAR1LMNA | |
| SCHEMBL14068528 | 0.82 | RAB9A (0.51) | MEN1KMT2AALDH1A1FFAR1LMNA | |
| SCHEMBL14261153 | 0.79 | LTA4H (0.52) | MEN1KMT2AALDH1A1RECQLFFAR1 | |
| SCHEMBL3418202 | 0.76 | FFAR1 (0.57) | MEN1KMT2AALDH1A1RECQLFFAR1 | |
| SCHEMBL3418207 | 0.76 | FFAR1 (0.57) | MEN1KMT2AALDH1A1RECQLFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008104875-A1 | OXAZOLIDINONES AS CHOLESTEROL ABSORPTION INHIBITORS | PFIZER PRODUCTS INC. (US) | 2008-09-04 | — | — | WO | disclosed |