Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.47 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.47 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.47 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14068528 | 1.00 | RAB9A (0.51) | RAB9ANPC1ALDH1A1PLAAT3PLAAT5 | |
| SCHEMBL14068463 | 0.94 | FFAR1 (0.52) | RAB9ANPC1ALDH1A1FFAR1SMN1; SMN2 | |
| SCHEMBL4745114 | 0.94 | FFAR1 (0.52) | RAB9ANPC1ALDH1A1FFAR1SMN1; SMN2 | |
| SCHEMBL4742525 | 0.82 | MEN1 (0.49) | RAB9ANPC1ALDH1A1FFAR1SMN1; SMN2 | |
| SCHEMBL14068292 | 0.82 | CXCL12 (0.47) | RAB9ANPC1FFAR1KMT2AMEN1 | |
| SCHEMBL3676320 | 0.72 | RAB9A (0.73) | RAB9ANPC1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL29237310 | 0.72 | FPR2 (0.57) | RAB9ANPC1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL2491083 | 0.70 | CNR2 (0.51) | RAB9ANPC1ALDH1A1TSHRCNR2 | |
| SCHEMBL24800806 | 0.70 | F2RL1 (0.74) | RAB9ANPC1ALDH1A1PLAAT3PLAAT5 | |
| SCHEMBL29237378 | 0.69 | ALDH1A1 (0.52) | RAB9ANPC1ALDH1A1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008104875-A1 | OXAZOLIDINONES AS CHOLESTEROL ABSORPTION INHIBITORS | PFIZER PRODUCTS INC. (US) | 2008-09-04 | — | — | WO | disclosed |