SCHEMBL4745370

SCHEMBL4745370

C[Si](C)(CCCc1ccccc1O)O[Si](C)(C)O[Si](C)(C)CCCc1ccccc1O

nearest known ligand 0.46

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MPO P05164 8/20 0.44
SLC6A4 P31645 2/20 0.44
TAAR1 Q96RJ0 1/20 0.43
MGLL Q99685 1/20 0.41
HTR1A P08908 1/20 0.40
HSPA5 P11021 1/20 0.39
IDO1 P14902 2/20 0.38
HRH3 Q9Y5N1 1/20 0.37
CYP2D6 P10635 1/20 0.36
TSHR P16473 1/20 0.36
HIF1A Q16665 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18563879 0.98 MPO (0.43) MPOSLC6A4TAAR1MGLLHTR1A
SCHEMBL16521079 0.98 MPO (0.43) MPOSLC6A4TAAR1MGLLHTR1A
SCHEMBL18198906 0.98 MPO (0.43) MPOSLC6A4TAAR1MGLLHTR1A
SCHEMBL15942683 0.98 MPO (0.43) MPOSLC6A4TAAR1MGLLHTR1A
SCHEMBL16521080 0.98 MPO (0.43) MPOSLC6A4TAAR1MGLLHTR1A
SCHEMBL18134209 0.98 MPO (0.43) MPOSLC6A4TAAR1MGLLHTR1A
SCHEMBL15396384 0.94 HTR1A (0.43) MPOSLC6A4TAAR1MGLLHTR1A
SCHEMBL8611487 0.94 MPO (0.40) MPOSLC6A4TAAR1MGLLHTR1A
SCHEMBL6684267 0.93 MPO (0.46) MPOSLC6A4TAAR1MGLLHTR1A
SCHEMBL12574831 0.90 MPO (0.44) MPOSLC6A4TAAR1MGLLHTR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240026074-A1 Polycarbonate Compositions Containing Titanium Dioxide and Glass Flakes Comprising a Titanium Dioxide Coating COVESTRO DEUTSCHLAND AG (DE) 2024-01-25 US disclosed
US-20240026074-A1 Polycarbonate Compositions Containing Titanium Dioxide and Glass Flakes Comprising a Titanium Dioxide Coating COVESTRO DEUTSCHLAND AG (DE) 2024-01-25 US disclosed
US-11795323-B2 Polycarbonate composition comprising talc COVESTRO DEUTSCHLAND AG (DE) 2023-10-24 US disclosed
US-11795323-B2 Polycarbonate composition comprising talc COVESTRO DEUTSCHLAND AG (DE) 2023-10-24 US disclosed
US-11708455-B2 Flame-retardant polycarbonate composition COVESTRO DEUTSCHLAND AG (DE) 2023-07-25 US disclosed
US-20230167296-A1 FLAME-RETARDANT POLYCARBONATE COMPOSITION COVESTRO DEUTSCHLAND AG (DE) 2023-06-01 US disclosed
US-20230125361-A1 FLAME-RETARDANT POLYCARBONATE COMPOSITION COVESTRO DEUTSCHLAND AG (DE) 2023-04-27 US disclosed
US-9557645-B2 Positive photosensitive resin composition, photo-curable dry film and method for producing same, layered product, patterning process, and substrate SHIN-ETSU CHEMICAL CO., LTD. (JP) 2017-01-31 US disclosed
US-9512276-B2 Phenol-modified polyorganosiloxane with reduced platinum content, method for preparing the same, and modifier for organic resin containing the same DOW CORNING TORAY CO., LTD. (JP) 2016-12-06 US disclosed
US-9400428-B2 Polymer compound, chemically amplified negative resist composition, photo-curable dry film and production method thereof, layered product, patterning process, and substrate SHIN-ETSU CHEMICAL CO., LTD. (JP) 2016-07-26 US disclosed
US-20100140537-A1 Curable Silicone Composition DOW CORNING TORAY CO., LTD. (JP) 2010-06-10 US disclosed
US-20100113667-A1 Curable Silicone Composition and Electronic Component DOW CORNING TORAY COMPANY, LTD. (JP) 2010-05-06 US disclosed
US-20100063185-A1 Curable Silicone Composition and Electronic Component DOW TORAY CO., LTD. (JP) 2010-03-11 US disclosed
US-20100022704-A1 Curable Silicone Composition And Cured Body Thereof DOW CORNING TORAY COMPANY, LTD. (JP) 2010-01-28 US disclosed
US-20090247681-A1 Curable Silicone Composition And Cured Product Therefrom DOW CORNING TORAY COMPANY, LTD. (JP) 2009-10-01 US disclosed
US-20090234078-A1 Organotrisiloxane, Preparation And Use In Curable Resin Composition DOW CORNING TORAY COMPANY, LTD. (JP) 2009-09-17 US disclosed
US-20090214870-A1 Curable Silicone Composition And Electronic Device Produced Therefrom DOW CORNING TORAY COMPANY, LTD. (JP) 2009-08-27 US disclosed
US-20090203837-A1 Curable Silicone Composition And Electronic Components DOW CORNING TORAY COMPANY, LTD. (JP) 2009-08-13 US disclosed
US-20080308225-A1 Adhesive composition suitable to be applied by screen printing SHIN-ETSU CHEMICAL CO., LTD. (JP) 2008-12-18 US disclosed
US-20080265439-A1 Die bonding agent and a semiconductor device made by using the same SHIN-ETSU CHEMICAL CO., LTD. 2008-10-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090234078-A1 Organotrisiloxane, Preparation And Use In Curable Resin Composition SEM1, CECR2, HRH3 MPO 1490/4885SLC6A4 4031/4885TAAR1 1381/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.