SCHEMBL4745377

SCHEMBL4745377

CC(C)(C(=O)O)N1CCNCC1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 2/20 0.38
CA12 O43570 1/20 0.38
CA1 P00915 1/20 0.38
CA9 Q16790 1/20 0.38
SIGMAR1 Q99720 2/20 0.38
HPGD P15428 1/20 0.37
CHKA P35790 1/20 0.37
CHRNB2 P17787 1/20 0.35
CHRNA3 P32297 1/20 0.35
CHRNA4 P43681 1/20 0.35
CHRNB3 Q05901 1/20 0.35
CHRNA6 Q15825 1/20 0.35
TSHR P16473 3/20 0.33
ALDH1A1 P00352 2/20 0.33
GAA P10253 1/20 0.33
PKM P14618 1/20 0.33
CHRM5 P08912 1/20 0.33
CHRM3 P20309 1/20 0.33
OPRD1 P41143 1/20 0.32
KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL25387507 0.98 HPGD (0.40) CA2CA12CA1CA9SIGMAR1
SCHEMBL14549470 0.82 ALDH1A1 (0.42) SIGMAR1TSHRALDH1A1
SCHEMBL7159906 0.82
SCHEMBL22045061 0.81 CA2 (0.38) CA2CA12CA1CA9SIGMAR1
Bicarbonate SCHEMBL6297564 0.81 CA2 (0.38) CA2CA12CA1CA9SIGMAR1
SCHEMBL3617365 0.80 SIGMAR1 (0.35) CA2CA12CA1CA9SIGMAR1
SCHEMBL28361029 0.80 SIGMAR1 (0.35) CA2CA12CA1CA9SIGMAR1
SCHEMBL1088468 0.79 SIGMAR1 (0.37) CA2CA12CA1CA9SIGMAR1
Hydrochloric Acid SCHEMBL28943394 0.79 HPGD (0.40) CA2CA12CA1CA9SIGMAR1
SCHEMBL17275988 0.79 SIGMAR1 (0.34) CA2CA12CA1CA9SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024208228-A1 NOVEL COMPOUNDS, COMPOSITIONS COMPRISING THE SAME AND USES THEREOF NUPHASE THERAPEUTICS (HANGZHOU) LIMITED., CO. (CN) 2024-10-10 WO disclosed
WO-2023172415-A1 SWEETENER COMPOSITIONS FIRMENICH INCORPORATED (US) 2023-09-14 WO disclosed
CN-111051605-B Artificial leather and method for producing same 乐金华奥斯株式会社 2023-04-18 CN disclosed
CN-104508555-B Photosensitive resin composition and photosensitive resin printing plate precursor 东丽株式会社 2020-02-11 CN disclosed
WO-2008107320-A1 PIPERIDINE AND PIPERAZINE DERIVATIVES USED AS ANTI-NEOPLASIC AGENTS OR CELL PROLIFERATION INHIBITORS CEREP (FR) 2008-09-12 WO disclosed
US-7173129-B2 Sulfonamide-substituted chalcone derivatives and their use to treat diseases ATHERO GENICS, INC. (US) 2007-02-06 US disclosed