Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.79 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.67 |
| ▸ | GAA | P10253 | 1/20 | 0.66 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.53 |
| ▸ | EGFR | P00533 | 1/20 | 0.53 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.53 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.51 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.51 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL835692 | 0.89 | PKM (1.00) | PKMALDH1A1GAARAPGEF4HSD11B1 | |
| SCHEMBL14486413 | 0.89 | PKM (1.00) | PKMALDH1A1GAARAPGEF4HSD11B1 | |
| SCHEMBL13074716 | 0.89 | PKM (1.00) | PKMALDH1A1GAARAPGEF4HSD11B1 | |
| SCHEMBL6392077 | 0.88 | PKM (0.59) | PKMALDH1A1MAPK1GAAMEN1 | |
| SCHEMBL13241565 | 0.86 | PKM (0.63) | PKMALDH1A1MAPK1CYP3A4GAA | |
| SCHEMBL931563 | 0.85 | HPGD (0.61) | PKMALDH1A1MAPK1MEN1KMT2A | |
| SCHEMBL10396881 | 0.83 | ALDH1A1 (0.73) | PKMALDH1A1MAPK1CYP3A4MEN1 | |
| SCHEMBL14148915 | 0.83 | PKM (0.86) | PKMALDH1A1GAARAPGEF4HSD11B1 | |
| SCHEMBL18069681 | 0.83 | PKM (0.86) | PKMALDH1A1GAARAPGEF4HSD11B1 | |
| SCHEMBL4617270 | 0.83 | HPGD (0.59) | PKMALDH1A1MAPK1GAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108623503-B | Green preparation method of vinyl sulfone derivative in water phase | 宁波大学 | 2020-01-03 | — | — | CN | disclosed |
| WO-2008107320-A1 | PIPERIDINE AND PIPERAZINE DERIVATIVES USED AS ANTI-NEOPLASIC AGENTS OR CELL PROLIFERATION INHIBITORS | CEREP (FR) | 2008-09-12 | — | — | WO | disclosed |
| EP-0083204-A2 | 2-Aminophenol derivatives and process for their preparation | ONO PHARMACEUTICAL CO., LTD. (JP) | 1983-07-06 | — | — | EP | disclosed |