Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.59 |
| ▸ | TDO2 | P48775 | 2/20 | 0.59 |
| ▸ | IDO2 | Q6ZQW0 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | MAPK14 | Q16539 | 8/20 | 0.53 |
| ▸ | DRD2 | P14416 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HTR6 | P50406 | 2/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | HTR7 | P34969 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
| ▸ | PARG | Q86W56 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6888074 | 0.83 | CHRNA7 (0.47) | IDO1TDO2IDO2MAPK14DRD2 | |
| SCHEMBL20511901 | 0.77 | KDM4E (0.63) | IDO1TDO2IDO2KDM4ENPC1 | |
| SCHEMBL7602321 | 0.76 | POLB (0.57) | KDM4ENPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL6886460 | 0.75 | CHRNA7 (0.52) | GAAPARG | |
| SCHEMBL17830817 | 0.74 | TDO2 (1.00) | IDO1TDO2IDO2NPC1RAB9A | |
| SCHEMBL16103944 | 0.74 | PARG (0.44) | IDO1TDO2IDO2NPC1MAPK14 | |
| SCHEMBL11922772 | 0.74 | PARG (0.44) | IDO1TDO2IDO2NPC1MAPK14 | |
| SCHEMBL17830806 | 0.74 | TDO2 (0.81) | IDO1TDO2IDO2KDM4ENPC1 | |
| SCHEMBL4745320 | 0.73 | KDM4E (0.56) | IDO1TDO2IDO2KDM4ENPC1 | |
| SCHEMBL4745451 | 0.73 | KDM4E (0.56) | IDO1TDO2IDO2KDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011045258-A1 | CONDENSED AZINE - DERIVATIVES FOR THE TREATMENT OF DISEASES RELATED TO THE ACETYLCHOLINE RECEPTOR | N.V. ORGANON (NL) | 2011-04-21 | — | — | WO | disclosed |