SCHEMBL474569

SCHEMBL474569

CCCCCCCCOC(=O)NNc1ccc(C)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 6/20 0.54
GAA P10253 3/20 0.54
HTT P42858 1/20 0.54
EPHX1 P07099 1/20 0.50
TSHR P16473 2/20 0.47
NPC1 O15118 6/20 0.46
RAB9A P51151 6/20 0.46
HPGD P15428 3/20 0.46
CYP1A2 P05177 1/20 0.46
CYP2C9 P11712 1/20 0.46
CYP2C19 P33261 1/20 0.46
ALDH1A1 P00352 2/20 0.46
CASP1 P29466 1/20 0.46
KDM4E B2RXH2 1/20 0.46
MAPT P10636 1/20 0.46
MAPK1 P28482 1/20 0.46
MCL1 Q07820 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
LMNA P02545 1/20 0.45
ACHE P22303 6/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL473102 0.94 SMN1; SMN2 (0.56) SMN1; SMN2GAAHTTNPC1RAB9A
SCHEMBL14052229 0.85 NPC1 (0.62) SMN1; SMN2TSHRNPC1RAB9AHPGD
SCHEMBL7924710 0.85 NPC1 (0.62) SMN1; SMN2TSHRNPC1RAB9AHPGD
SCHEMBL21059214 0.85 NPC1 (0.62) SMN1; SMN2TSHRNPC1RAB9AHPGD
SCHEMBL4840984 0.85 NPC1 (0.62) SMN1; SMN2TSHRNPC1RAB9AHPGD
SCHEMBL21059194 0.83 RAB9A (0.64) SMN1; SMN2TSHRNPC1RAB9AHPGD
SCHEMBL1625209 0.80 GAA (0.71) SMN1; SMN2GAATSHRNPC1RAB9A
SCHEMBL13931805 0.79 TSHR (0.56) SMN1; SMN2EPHX1TSHRNPC1RAB9A
SCHEMBL13931799 0.79 TSHR (0.56) SMN1; SMN2EPHX1TSHRNPC1RAB9A
SCHEMBL13931804 0.79 TSHR (0.56) SMN1; SMN2EPHX1TSHRNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2412703-B1 URETHANE COMPOUND AND PROCESS FOR PRODUCTION THEREOF, AND ISOCYANATE AND PROCESS FOR PRODUCTION THEREOF MITSUI CHEMICALS INC (JP) 2016-06-29 EP disclosed
US-9150502-B2 Urethane compound and method for producing the same, and isocyanate and method for producing the same MITSUI CHEMICALS, INC. (JP) 2015-10-06 US disclosed
EP-2412703-A1 URETHANE COMPOUND AND PROCESS FOR PRODUCTION THEREOF, AND ISOCYANATE AND PROCESS FOR PRODUCTION THEREOF Mitsui Chemicals, Inc. (JP) 2012-02-01 EP disclosed
US-20120010427-A1 URETHANE COMPOUND AND METHOD FOR PRODUCING THE SAME, AND ISOCYANATE AND METHOD FOR PRODUCING THE SAME MITSUI CHEMICALS, INC. 2012-01-12 US disclosed