SCHEMBL474570

SCHEMBL474570

CCCCCCCCOC(=O)NNCc1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.53
NPC1 O15118 2/20 0.53
RAB9A P51151 2/20 0.53
TSHR P16473 3/20 0.51
LMNA P02545 2/20 0.51
ALDH1A1 P00352 2/20 0.51
EPHX2 P34913 1/20 0.51
CYP3A4 P08684 2/20 0.49
MAPK1 P28482 2/20 0.49
TDP1 Q9NUW8 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
TP53 P04637 1/20 0.49
EPHX1 P07099 1/20 0.49
CTSK P43235 2/20 0.47
CETP P11597 3/20 0.47
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
CYP1A2 P05177 1/20 0.46
CYP2C19 P33261 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL473103 0.94 TDP1 (0.55) SMN1; SMN2NPC1RAB9ATSHRLMNA
SCHEMBL9937386 0.86 SMN1; SMN2 (0.47) SMN1; SMN2NPC1RAB9ATSHRLMNA
SCHEMBL28969034 0.85 NPC1 (0.63) SMN1; SMN2NPC1RAB9ATSHRLMNA
SCHEMBL28105060 0.85 NPC1 (0.63) SMN1; SMN2NPC1RAB9ATSHRLMNA
SCHEMBL8773507 0.85 NPC1 (0.63) SMN1; SMN2NPC1RAB9ATSHRLMNA
SCHEMBL28969065 0.85 NPC1 (0.63) SMN1; SMN2NPC1RAB9ATSHRLMNA
SCHEMBL29106946 0.85 NPC1 (0.63) SMN1; SMN2NPC1RAB9ATSHRLMNA
SCHEMBL27621693 0.85 NPC1 (0.63) SMN1; SMN2NPC1RAB9ATSHRLMNA
SCHEMBL5803249 0.84 NPC1 (0.62) SMN1; SMN2NPC1RAB9ATSHRLMNA
SCHEMBL7434407 0.82 GAA (0.60) SMN1; SMN2NPC1RAB9ATSHRLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2412703-B1 URETHANE COMPOUND AND PROCESS FOR PRODUCTION THEREOF, AND ISOCYANATE AND PROCESS FOR PRODUCTION THEREOF MITSUI CHEMICALS INC (JP) 2016-06-29 EP disclosed
US-9150502-B2 Urethane compound and method for producing the same, and isocyanate and method for producing the same MITSUI CHEMICALS, INC. (JP) 2015-10-06 US disclosed
EP-2412703-A1 URETHANE COMPOUND AND PROCESS FOR PRODUCTION THEREOF, AND ISOCYANATE AND PROCESS FOR PRODUCTION THEREOF Mitsui Chemicals, Inc. (JP) 2012-02-01 EP disclosed
US-20120010427-A1 URETHANE COMPOUND AND METHOD FOR PRODUCING THE SAME, AND ISOCYANATE AND METHOD FOR PRODUCING THE SAME MITSUI CHEMICALS, INC. 2012-01-12 US disclosed