Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | RET | P07949 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16131321 | 0.77 | RET (0.44) | ALDH1A1SMN1; SMN2RET | |
| SCHEMBL3948947 | 0.72 | CES1 (0.30) | — | |
| SCHEMBL11058273 | 0.71 | RET (0.40) | ALDH1A1RET | |
| SCHEMBL156273 | 0.69 | POLB (0.39) | ALDH1A1 | |
| SCHEMBL30424597 | 0.66 | HTR2A (0.38) | — | |
| SCHEMBL5574454 | 0.65 | DRD2 (0.40) | — | |
| SCHEMBL5679199 | 0.64 | MAOA (0.47) | SMN1; SMN2 | |
| SCHEMBL63929 | 0.63 | HTR2A (0.34) | ALDH1A1RET | |
| SCHEMBL29069610 | 0.62 | HTR2A (0.37) | — | |
| SCHEMBL10739253 | 0.61 | RET (0.37) | ALDH1A1RET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008113795-A1 | COMPOUNDS WHICH POTENTIATE AMPA RECEPTOR AND USES THEREOF IN MEDICINE | GLAXO GROUP LIMITED (GB) | 2008-09-25 | — | — | WO | disclosed |