Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 2/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | DRD5 | P21918 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | GPR3 | P46089 | 2/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.36 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16131321 | 0.78 | RET (0.44) | POLBDRD2DRD3HTR2AALDH1A1 | |
| SCHEMBL1140650 | 0.77 | GPR3 (0.37) | POLBDRD1DRD3GPR3HTR2A | |
| SCHEMBL9403771 | 0.77 | KMT2A (0.44) | POLBDRD1DRD2DRD4DRD5 | |
| SCHEMBL5679199 | 0.77 | MAOA (0.47) | HDAC3HDAC4HDAC7HDAC8HDAC6 | |
| SCHEMBL12043727 | 0.74 | GPR3 (0.39) | POLBDRD1DRD3GPR3HTR2A | |
| SCHEMBL29090326 | 0.73 | GPR3 (0.41) | POLBDRD1DRD3GPR3HTR2A | |
| SCHEMBL5732470 | 0.72 | HTR2A (0.38) | POLBDRD1DRD3GPR3HTR2A | |
| SCHEMBL13327258 | 0.72 | GPR3 (0.44) | POLBDRD1DRD3GPR3HTR2A | |
| SCHEMBL28831999 | 0.71 | CA1 (0.40) | POLBGPR3HTR2AHDAC3HDAC4 | |
| SCHEMBL6805568 | 0.70 | ALDH1A1 (0.46) | POLBCA1CA2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 325 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117295727-A | Pyridazinones as PARP7 inhibitors | 中山优理生物医药有限公司 | 2023-12-26 | — | — | CN | claimed |
| CN-115916786-A | Manufacture of compounds and compositions for inhibiting SHP2 activity | 诺华股份有限公司 | 2023-04-04 | — | — | CN | claimed |
| WO-2022253101-A1 | PYRIDAZINONE COMPOUND AS PARP7 INHIBITOR | 上海优理惠生医药有限公司 | 2022-12-08 | — | — | WO | claimed |
| EP-2471944-B1 | Novel peptidase substrates | BIOMERIEUX SA (FR) | 2016-09-14 | — | — | EP | claimed |
| CN-103178213-B | Organic light-emitting display device and manufacture method thereof | LG DISPLAY CO., LTD. (KR) | 2015-11-18 | — | — | CN | claimed |
| CN-103998518-A | Highly functionalized resin blends | HENKEL CORP | 2014-08-20 | — | — | CN | claimed |
| CN-103382321-A | Photocurable elastomer compositions | HENKEL CORP | 2013-11-06 | — | — | CN | claimed |
| CN-103178213-A | Organic light emitting display device and method for fabricating the same | LG DISPLAY CO LTD | 2013-06-26 | — | — | CN | claimed |
| WO-2012016935-A1 | SEVEN CARBON (C-7) SUGARS DERIVATIVES AND THEIR USE | CENTRUM FÜR ANGEWANDTE NANOTECHNOLOGIE (CAN) GMBH (DE) | 2012-02-09 | — | — | WO | claimed |
| CN-101511959-A | photocurable elastomer composition | HENKEL CORP (US) | 2009-08-19 | — | — | CN | claimed |
| US-20060189555-A1 | Pyrroles substituted by oligonucleotides | APIBIO (FR) | 2006-08-24 | — | — | US | claimed |
| EP-1474430-B1 | BI-FUNCTIONALISED METALLOCENES USE FOR MARKING BIOLOGICAL MOLECULES | BIOMERIEUX SA (FR) | 2006-01-25 | — | — | EP | claimed |
| CN-1209350-C | Process for synthesizing L-N-protective group-azacyclobutane-2-carboxylic acid | SHANGHAI INST OF METERIA MEDIC (CN) | 2005-07-06 | — | — | CN | claimed |
| US-20050038234-A1 | Such as 1-[3-O-dimethoxytritylpropyl]-1'-[3'-O-(2-cyanoethyl-N,N-diisopropylphosphoramidityl)propyl]ferrocene for solid phase synthesis of oligonucleotides/peptides | BIO MERIEUX | 2005-02-17 | — | — | US | claimed |
| CN-1166704-C | Anti-reflection coating polymer and preparing method thereof | �ִ����Ӳ�ҵ��ʽ���� | 2004-09-15 | — | — | CN | claimed |
| CN-1260355-A | Anti-reflection coating polymer and preparing method thereof | HYUNDAI ELECTRONICS IND (KR) | 2000-07-19 | — | — | CN | claimed |
| US-5663030-A | A PHENYL OR NORBORNANE DERIVATIVE AS AN ADDITIVE TO REDUCE HEAT AND ENERGY REQUIRED TO FUSE THE TONER AND TO REDUCE JAMMING OF THE EQUIPMENT | XEROX CORPORATION (US) | 1997-09-02 | — | — | US | claimed |
| US-5334506-A | Phenoxazines bonded to peptide substrate, cleavable by enzyme; | BEHRINGWERKE AKTIENGESELLSCHAFT (DE) | 1994-08-02 | — | — | US | claimed |
| CN-1020106-C | Process for pyrimidine derivatives | HOFFMANN LA ROCHE (CH) | 1993-03-17 | — | — | CN | claimed |
| US-5097014-A | Phenoxazonium chromogens for the color blue | BEHRINGWERKE AKTIENGESELLSCHAFT (DE) | 1992-03-17 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050038234-A1 | Such as 1-[3-O-dimethoxytritylpropyl]-1'-[3'-O-(2-cyanoethyl-N,N-diisopropylphosphoramidityl)propyl]ferrocene for solid phase synthesis of oligonucleotides/peptides | FTH1, DOHH, NSUN2 | POLB 49/4885DRD1 2913/4885DRD2 3141/4885 |
| US-20060189555-A1 | Pyrroles substituted by oligonucleotides | POLR2E, NSUN3, RNGTT | POLB 87/4885DRD1 900/4885DRD2 1254/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.