Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 4/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.35 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.33 |
| ▸ | KCNQ4 | P56696 | 1/20 | 0.33 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.33 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | AGTR1 | P30556 | 4/20 | 0.33 |
| ▸ | AGTR2 | P50052 | 4/20 | 0.33 |
| ▸ | RIPK3 | Q9Y572 | 2/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.32 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4745710 | 0.86 | KCNA5 (0.35) | KCNA5AKR1B1KCNQ4KCNQ5AAK1 | |
| SCHEMBL4746002 | 0.81 | AKR1B1 (0.40) | AKR1B1PTGER1KCNQ4KCNQ5AAK1 | |
| SCHEMBL23985264 | 0.73 | MAPT (0.39) | KCNQ4KCNQ5ALDH1A1P2RX3 | |
| SCHEMBL4749155 | 0.69 | AAK1 (0.36) | KCNQ4KCNQ5AAK1P2RX3 | |
| SCHEMBL4749154 | 0.69 | AAK1 (0.36) | KCNQ4KCNQ5AAK1P2RX3 | |
| SCHEMBL857284 | 0.67 | HTT (0.55) | KCNQ4KCNQ5ALDH1A1 | |
| SCHEMBL22941300 | 0.67 | KCNQ4 (0.47) | KCNQ4KCNQ5AAK1 | |
| SCHEMBL12791296 | 0.67 | P2RX7 (0.46) | KCNA5 | |
| SCHEMBL4301168 | 0.65 | AAK1 (0.50) | KCNQ4KCNQ5AAK1ALDH1A1 | |
| SCHEMBL197145 | 0.65 | HDAC1 (0.55) | KCNQ4KCNQ5AAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008124518-A1 | OXO-DIHYDROISOINDOLE SULFONAMIDE COMPOUNDS AS MODULATORS OF THE CCK2 RECEPTOR | JANSSEN PHARMACEUTICA N.V. (BE) | 2008-10-16 | — | — | WO | disclosed |