SCHEMBL474592

SCHEMBL474592

C[C@@]1(O)[C@H](O)[C@@H](CO)O[C@H]1n1ccc(=O)[nH]c1=O

nearest known ligand 0.62

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
P2RY2 P41231 3/20 0.62
P2RY4 P51582 1/20 0.62
SLC29A1 Q99808 2/20 0.57
SLC28A1 O00337 1/20 0.57
SLC28A2 O43868 1/20 0.57
SLC28A3 Q9HAS3 1/20 0.57
ADORA2A P29274 2/20 0.44
POLA1 P09884 1/20 0.44
P2RY14 Q15391 3/20 0.42
PDE4D Q08499 1/20 0.41
PDE3A Q14432 1/20 0.41
P2RY6 Q15077 2/20 0.41
DUT P33316 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10265714 1.00 P2RY2 (0.62) P2RY2P2RY4SLC29A1SLC28A1SLC28A2
SCHEMBL10159392 1.00 P2RY2 (0.62) P2RY2P2RY4SLC29A1SLC28A1SLC28A2
SCHEMBL19537371 1.00 P2RY2 (0.62) P2RY2P2RY4SLC29A1SLC28A1SLC28A2
SCHEMBL19534525 1.00 P2RY2 (0.62) P2RY2P2RY4SLC29A1SLC28A1SLC28A2
SCHEMBL12621455 1.00 P2RY2 (0.62) P2RY2P2RY4SLC29A1SLC28A1SLC28A2
SCHEMBL12658368 1.00 P2RY2 (0.62) P2RY2P2RY4SLC29A1SLC28A1SLC28A2
SCHEMBL23880678 1.00 P2RY2 (0.62) P2RY2P2RY4SLC29A1SLC28A1SLC28A2
SCHEMBL12939575 1.00 P2RY2 (0.62) P2RY2P2RY4SLC29A1SLC28A1SLC28A2
SCHEMBL14853791 1.00 P2RY2 (0.62) P2RY2P2RY4SLC29A1SLC28A1SLC28A2
SCHEMBL16169491 1.00 P2RY2 (0.62) P2RY2P2RY4SLC29A1SLC28A1SLC28A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 714 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12083185-B2 Small polymeric carriers for delivery of agents University of Pittsburgh—of the Commonwealth System of Higher Education (US) 2024-09-10 US claimed
US-20240226335-A9 RNA Containing Modified Nucleosides and Methods of Use Thereof THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA 2024-07-11 US claimed
US-20240131194-A1 RNA Containing Modified Nucleosides and Methods of Use Thereof UNIV PENNSYLVANIA (US) 2024-04-25 US claimed
WO-2021224646-A1 METHOD FOR THE TREATMENT OF RNA VIRUS INVOLVED DISEASES TURNSOLE BIOLOGICS LLC. (HU) 2021-11-11 WO claimed
US-20210330808-A1 SMALL POLYMERIC CARRIERS FOR DELIVERY OF AGENTS NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2021-10-28 US claimed
EP-3863609-A1 SMALL POLYMERIC CARRIERS FOR DELIVERY OF AGENTS University of Pittsburgh - Of the Commonwealth System of Higher Education (US) 2021-08-18 EP claimed
US-11021497-B2 Compositions and methods for synthesis of phosphorylated molecules THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2021-06-01 US claimed
CN-112823000-A Small polymer carriers for agent delivery 联邦高等教育系统匹兹堡大学 2021-05-18 CN claimed
US-20200239500-A1 Compositions and Methods for Synthesis of Phosphorylated Molecules THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2020-07-30 US claimed
CN-111317739-A Application of erythromycin estolate in preparation of medicine for specifically inhibiting virus infection 复旦大学 2020-06-23 CN claimed
WO-2013159103-A1 PROGRAMMING AND REPROGRAMMING OF CELLS WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH (US) 2013-10-24 WO claimed
WO-2013106344-A1 2 '-C-METHYL NUCLEOSIDES CONTAINING A CYCLIC PHOSPHATE DIESTER OF 1, 3-PROPANEDIOL (2-OXO-[1, 3, 2]-DIOXAPHOSPHORINANE) AT POSITION 5' LIGAND PHARMACEUTICALS, INC. (US) 2013-07-18 WO claimed
EP-2432792-A1 N- [ (2 ' R) -2 ' -DEOXY-2 ' -FLUORO-2 ' -METHYL-P-PHENYL-5 ' -URIDYLYL]-L-ALANINE 1-METHYLETHYL ESTER AND PROCESS FOR ITS PRODUCTION Pharmasset, Inc. (US) 2012-03-28 EP claimed
WO-2010135569-A1 N- [ (2 ' R) -2 ' -DEOXY-2 ' -FLUORO-2 ' -METHYL-P-PHENYL-5 ' -URIDYLYL] -L-ALANINE 1-METHYLETHYL ESTER AND PROCESS FOR ITS PRODUCTION PHARMASSET, INC. (US) 2010-11-25 WO claimed
US-7598230-B2 For the treatment of viral infections, microbial infections, and proliferative disorders; contain di- or triphosphate moeity mimetics, such as those containing boron anions BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) 2009-10-06 US claimed
US-20070259832-A1 Nucleotide mimics and their prodrugs BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) 2007-11-08 US claimed
EP-1501850-A2 NUCLEOSIDE DERIVATIVES FOR TREATING HEPATITIS C VIRUS INFECTION GENELABS TECHNOLOGIES, INC. (US) 2005-02-02 EP claimed
US-20040063658-A1 Nucleoside derivatives for treating hepatitis C virus infection GENELABS TECHNOLOGIES, INC. 2004-04-01 US claimed
US-20040059104-A1 Nucleotide mimics and their prodrugs BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) 2004-03-25 US claimed
WO-2003093290-A2 NUCLEOSIDE DERIVATIVES FOR TREATING HEPATITIS C VIRUS INFECTION GENELABS TECHNOLOGIES, INC. (US) 2003-11-13 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040063658-A1 Nucleoside derivatives for treating hepatitis C virus infection HAVCR2, PNP, NTPCR P2RY2 2276/4885P2RY4 1503/4885SLC29A1 38/4885
US-20070259832-A1 Nucleotide mimics and their prodrugs NUDT14, ENTPD5, MTAP P2RY2 104/4885P2RY4 46/4885SLC29A1 19/4885
US-20200239500-A1 Compositions and Methods for Synthesis of Phosphorylated Molecules PIK3CA, CHAMP1, TYMP P2RY2 531/4885P2RY4 354/4885SLC29A1 498/4885
US-12083185-B2 Small polymeric carriers for delivery of agents CD44, PGF, SLC46A1 P2RY2 4632/4885P2RY4 4629/4885SLC29A1 552/4885
US-11021497-B2 Compositions and methods for synthesis of phosphorylated molecules PIK3CA, CHAMP1, TYMP P2RY2 531/4885P2RY4 354/4885SLC29A1 498/4885
US-20040059104-A1 Nucleotide mimics and their prodrugs NUDT14, ENTPD5, MTAP P2RY2 104/4885P2RY4 46/4885SLC29A1 19/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.