SCHEMBL4745944

SCHEMBL4745944

C(=N/Nc1nnn[nH]1)\c1cccc2c1[nH]c1ccccc12

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ GAA P10253 13/20 0.41
▸ MAPT P10636 13/20 0.41
▸ KMT2A Q03164 8/20 0.41
▸ NPC1 O15118 7/20 0.41
▸ RAB9A P51151 6/20 0.41
▸ SMN1; SMN2 Q16637 6/20 0.41
▸ MEN1 O00255 6/20 0.41
▸ TDP1 Q9NUW8 5/20 0.41
▸ HTT P42858 3/20 0.41
▸ LMNA P02545 3/20 0.41
▸ MPO P05164 1/20 0.41
▸ GFER P55789 1/20 0.41
▸ MAP4K4 O95819 1/20 0.41
▸ FLT3 P36888 1/20 0.41
▸ SYK P43405 1/20 0.41
▸ MAP4K2 Q12851 1/20 0.41
▸ AURKB Q96GD4 1/20 0.41
▸ CLK4 Q9HAZ1 1/20 0.41
▸ IRAK4 Q9NWZ3 1/20 0.41
▸ MAP3K20 Q9NYL2 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4745948 1.00 GAA (0.41) GAAMAPTKMT2ANPC1RAB9A
SCHEMBL13381802 0.75 KDM4E (0.58) GAAMAPTKMT2ANPC1RAB9A
SCHEMBL4743123 0.74 GAA (0.42) GAAMAPTKMT2ANPC1RAB9A
SCHEMBL4743125 0.74 GAA (0.42) GAAMAPTKMT2ANPC1RAB9A
SCHEMBL15558826 0.71 CTH (0.54) GAAMAPTKMT2ANPC1RAB9A
SCHEMBL15558824 0.71 CTH (0.54) GAAMAPTKMT2ANPC1RAB9A
SCHEMBL3792578 0.70 HCRTR1 (0.46) GAAMAPTKMT2ANPC1RAB9A
SCHEMBL3792577 0.70 HCRTR1 (0.46) GAAMAPTKMT2ANPC1RAB9A
SCHEMBL17201977 0.70 HPGD (0.53) MAPTKMT2AMEN1HTTGFER
SCHEMBL4743127 0.69 KIF11 (0.37) GAAMAPTKMT2ANPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1283448-B1 Electrophotographic organophotoreceptors with charge transport compounds SAMSUNG ELECTRONICS CO LTD (KR) 2008-11-05 — — EP disclosed
US-7358014-B2 Electrophotographic organophotoreceptors with novel charge transport compounds SAMSUNG ELECTRONICS CO., LTD. (KR) 2008-04-15 — — US disclosed
US-20050112490-A1 Electrophotographic organophotoreceptors with novel charge transport compounds SAMSUNG ELECTRONICS CO., LTD. 2005-05-26 — — US disclosed
US-20030113132-A1 Electrophotographic organophotoreceptors with novel charge transport compounds SAMSUNG INFORMATION SYSTEMS AMERICA 2003-06-19 — — US disclosed
EP-1283448-A2 Electrophotographic organophotoreceptors with charge transport compounds Samsung Electronics Co., Ltd. (KR) 2003-02-12 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030113132-A1 Electrophotographic organophotoreceptors with novel charge transport compounds SLC43A1, SLC18A2, SLC1A1 GAA 2883/4885MAPT 4385/4885KMT2A 2531/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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