SCHEMBL4746034

SCHEMBL4746034

CCOC(=O)c1ccc(NC=O)cc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 8/20 0.62
SMN1; SMN2 Q16637 7/20 0.62
KMT2A Q03164 6/20 0.62
MEN1 O00255 5/20 0.62
MAPT P10636 5/20 0.62
NPC1 O15118 4/20 0.62
MAPK1 P28482 2/20 0.62
HPGD P15428 2/20 0.59
RECQL P46063 1/20 0.59
ALDH1A1 P00352 3/20 0.58
CYP1A2 P05177 2/20 0.58
CYP3A4 P08684 2/20 0.58
CYP2C19 P33261 1/20 0.58
CA1 P00915 2/20 0.58
CA2 P00918 2/20 0.58
TSHR P16473 1/20 0.58
CA12 O43570 1/20 0.58
ESR1 P03372 1/20 0.58
CA7 P43166 1/20 0.58
CA9 Q16790 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5545353 0.87 ALDH1A1 (0.60) RAB9ASMN1; SMN2KMT2AMEN1MAPT
SCHEMBL4013627 0.87 RAB9A (0.59) RAB9ASMN1; SMN2KMT2AMEN1MAPT
SCHEMBL11915500 0.85 RAB9A (0.61) RAB9ASMN1; SMN2KMT2AMEN1MAPT
SCHEMBL27516313 0.85 RAB9A (0.61) RAB9ASMN1; SMN2KMT2AMEN1MAPT
SCHEMBL5531110 0.84 HPGD (0.67) RAB9ASMN1; SMN2KMT2AMEN1MAPT
SCHEMBL14311838 0.83 RAB9A (0.59) RAB9ASMN1; SMN2KMT2AMEN1MAPT
SCHEMBL12124929 0.82 RAB9A (0.69) RAB9ASMN1; SMN2KMT2AMEN1MAPT
SCHEMBL2345447 0.82 ALDH1A1 (0.60) RAB9ASMN1; SMN2KMT2AMEN1MAPT
SCHEMBL6934601 0.82 ALDH1A1 (0.62) RAB9ASMN1; SMN2MAPTNPC1MAPK1
SCHEMBL87450 0.81 CA1 (0.83) RAB9ASMN1; SMN2KMT2AMEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115138311-A Method for enhancing liquid substance energy by utilizing electromagnetic wave technology 重庆普康生物科技有限公司 2022-10-04 CN claimed
US-8338401-B2 Coumarin-amide derivatives and its preparation, said drug composition and its use INSTITUTE OF MATERIA MEDICA CHINESE ACADEMY OF MEDICAL SCIENCES (CN) 2012-12-25 US claimed
EP-1189891-A1 TRIAZOLE COMPOUNDS AND COMBINATORIAL LIBRARIES THEREOF LION Bioscience AG (DE) 2002-03-27 EP claimed
US-6362342-B1 BIOSYNTHESIS; DRUG LIBRARIES LION BIOSCIENCE AG (DE) 2002-03-26 US claimed
WO-2001000594-A1 TRIAZOLE COMPOUNDS AND COMBINATORIAL LIBRARIES THEREOF LION BIOSCIENCE AG (DE) 2001-01-04 WO claimed
EP-3143026-B1 COMPOUNDS AND COMPOSITIONS FOR INDUCING CHONDROGENESIS NOVARTIS AG (CH) 2024-07-10 EP disclosed
CN-115138311-A Method for enhancing liquid substance energy by utilizing electromagnetic wave technology 重庆普康生物科技有限公司 2022-10-04 CN disclosed
CN-115138311-A Method for enhancing liquid substance energy by utilizing electromagnetic wave technology 重庆普康生物科技有限公司 2022-10-04 CN disclosed
EP-2570418-A2 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles compound OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2013-03-20 EP disclosed
CN-101481331-B N,N'-bis(4-ethoxy carbonyl phenyl)-N'-benzyl formamidine CHANGZHOU SUNLIGHT PHARM CO LTD 2013-02-13 CN disclosed
EP-1555267-B1 2,3-DIHYDRO-6-NITROIMIDAZO[2,1-b]OXAZOLES OTSUKA PHARMA CO LTD (JP) 2013-01-16 EP disclosed
EP-1692114-B1 NOVEL BENZIMIDAZOLE AND IMIDAZOPYRIDINE DERIVATIVES AND USE THEREOF AS A MEDICAMENT IPSEN PHARMA (FR) 2010-09-22 EP disclosed
US-4927925-A Piperidine compounds and their use as thermal stabilizers CIBA-GEIGY CORPORATION (US) 1990-05-22 US disclosed
EP-0337490-A2 Silver halide light-sensitive photographic material Fuji Photo Film Co., Ltd. (JP) 1989-10-18 EP disclosed
US-4803234-A Piperidine compounds and their use as anti-oxidative, light or thermal induced degradation agents CIBA-GEIGY CORPORATION (US) 1989-02-07 US disclosed
US-4594313-A Containing hetero rings FUJI PHOTO FILM CO., LTD. (JP) 1986-06-10 US disclosed
EP-0003259-B1 N-FORMYLANILIDO AROMATIC COMPOUNDS, PROCESS FOR THEIR PREPARATION AND PROCESS FOR THE PREPARATION OF THE CORRESPONDING N-PHENYL AROMATIC AMINO COMPOUNDS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1982-03-24 EP disclosed
US-4292446-A N-FORMYLANILINO AROMATICS, DIPHENYLAMINE INTERMEDIATES, PESTICIDES, PREPARATION FROM FORMANILIDES AND HALOAROMATICS IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1981-09-29 US disclosed
EP-0003259-A1 N-Formylanilido aromatic compounds, process for their preparation and process for the preparation of the corresponding N-phenyl aromatic amino compounds IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1979-08-08 EP disclosed
US-4021471-A Formamidines useful as ultraviolet light absorbers GIVAUDAN CORPORATION (US) 1977-05-03 US disclosed