Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | ADH1B | P00325 | 1/20 | 0.31 |
| ▸ | ADH1C | P00326 | 1/20 | 0.31 |
| ▸ | ADH1A | P07327 | 1/20 | 0.31 |
| ▸ | ADH4 | P08319 | 1/20 | 0.31 |
| ▸ | ADH7 | P40394 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31008624 | 0.92 | SIGMAR1 (0.37) | TSHRSMN1; SMN2HTTSIGMAR1ALDH1A1 | |
| SCHEMBL20193432 | 0.86 | HTT (0.30) | SMN1; SMN2HTT | |
| SCHEMBL10045265 | 0.85 | TSHR (0.42) | TSHRSMN1; SMN2HTTSIGMAR1ALDH1A1 | |
| SCHEMBL21023376 | 0.84 | ALDH1A1 (0.44) | TSHRALDH1A1 | |
| SCHEMBL3664048 | 0.83 | — | — | |
| SCHEMBL8262545 | 0.83 | — | — | |
| SCHEMBL23639484 | 0.83 | TSHR (0.41) | TSHRALDH1A1ADH1BADH1CADH1A | |
| SCHEMBL18663433 | 0.82 | EPHX1 (0.35) | SIGMAR1 | |
| SCHEMBL18784682 | 0.81 | ADH1B (0.53) | TSHRALDH1A1ADH1BADH1CADH1A | |
| SCHEMBL11607530 | 0.81 | ADH1B (0.53) | TSHRALDH1A1ADH1BADH1CADH1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008112636-A1 | CHAIN EXTENDERS | ALBEMARLE CORPORATION (US) | 2008-09-18 | — | — | WO | disclosed |