Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EBP | Q15125 | 1/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.54 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | BCL2 | P10415 | 1/20 | 0.39 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4746224 | 0.82 | DRD2 (0.43) | PPARGPPARADRD2DRD4DRD3 | |
| SCHEMBL4310502 | 0.81 | EBP (0.81) | EBPSIGMAR1DRD3LMNAHTT | |
| SCHEMBL8770550 | 0.78 | LMNA (0.47) | EBPSIGMAR1LMNAHTTNPSR1 | |
| SCHEMBL7390013 | 0.78 | HRH3 (0.53) | DRD2DRD4DRD3HRH3 | |
| SCHEMBL6752147 | 0.78 | HRH3 (0.53) | DRD2DRD4DRD3HRH3 | |
| SCHEMBL10384122 | 0.78 | HRH3 (0.53) | DRD2DRD4DRD3HRH3 | |
| SCHEMBL7621718 | 0.78 | HRH3 (0.53) | DRD2DRD4DRD3HRH3 | |
| SCHEMBL1172364 | 0.76 | DRD4 (0.53) | DRD2DRD4DRD3HRH3 | |
| SCHEMBL4747589 | 0.73 | HTT (0.53) | EBPSIGMAR1LMNAHTTNPSR1 | |
| SCHEMBL17233002 | 0.73 | HRH3 (0.49) | DRD2DRD4DRD3SMN1; SMN2HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008107320-A1 | PIPERIDINE AND PIPERAZINE DERIVATIVES USED AS ANTI-NEOPLASIC AGENTS OR CELL PROLIFERATION INHIBITORS | CEREP (FR) | 2008-09-12 | — | — | WO | disclosed |