Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 11/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.39 |
| ▸ | ESRRG | P62508 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4746221 | 0.82 | EBP (0.54) | DRD2DRD4DRD3HRH3PPARG | |
| SCHEMBL8707721 | 0.80 | EBP (0.60) | DRD3HRH3ESRRG | |
| SCHEMBL7621718 | 0.80 | HRH3 (0.53) | DRD2DRD4DRD3HRH3 | |
| SCHEMBL6752147 | 0.80 | HRH3 (0.53) | DRD2DRD4DRD3HRH3 | |
| SCHEMBL10384122 | 0.80 | HRH3 (0.53) | DRD2DRD4DRD3HRH3 | |
| SCHEMBL7390013 | 0.80 | HRH3 (0.53) | DRD2DRD4DRD3HRH3 | |
| SCHEMBL1172364 | 0.78 | DRD4 (0.53) | DRD2DRD4DRD3HRH3 | |
| SCHEMBL4745368 | 0.76 | SMN1; SMN2 (0.62) | KCNA3 | |
| SCHEMBL17233002 | 0.75 | HRH3 (0.49) | DRD2DRD4DRD3HRH3 | |
| SCHEMBL4747583 | 0.75 | LTA4H (0.50) | DRD2DRD4DRD3HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008107320-A1 | PIPERIDINE AND PIPERAZINE DERIVATIVES USED AS ANTI-NEOPLASIC AGENTS OR CELL PROLIFERATION INHIBITORS | CEREP (FR) | 2008-09-12 | — | — | WO | disclosed |