Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 15/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 7/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4746913 | 0.83 | HDAC2 (0.52) | HDAC1HDAC2 | |
| SCHEMBL4746557 | 0.81 | MAPT (0.41) | — | |
| SCHEMBL4746560 | 0.81 | MAPT (0.41) | — | |
| SCHEMBL23236208 | 0.71 | HDAC1 (0.38) | HDAC1HDAC2HDAC3 | |
| SCHEMBL27029836 | 0.70 | MAPT (0.40) | HDAC1HDAC2HDAC3 | |
| SCHEMBL2590028 | 0.70 | HDAC2 (0.51) | HDAC1HDAC2HDAC3 | |
| SCHEMBL15551319 | 0.69 | HDAC2 (0.51) | HDAC1HDAC2HDAC3HTT | |
| SCHEMBL5368473 | 0.69 | DRD2 (0.55) | HTTL3MBTL1 | |
| SCHEMBL4746315 | 0.69 | TP53 (0.37) | HDAC1HDAC2HDAC3 | |
| SCHEMBL3958147 | 0.68 | HTT (0.44) | HTTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008119718-A1 | COMPOUNDS WHICH HAVE ACTIVITY AT M1 RECEPTOR AND THEIR USES IN MEDICINE | GLAXO GROUP LIMITED (GB) | 2008-10-09 | — | — | WO | disclosed |