Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | GRK6 | P43250 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4746560 | 1.00 | MAPT (0.41) | MAPTCYP3A4TSHRKAT2BALDH1A1 | |
| SCHEMBL4749627 | 0.85 | MAPT (0.47) | MAPTALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL3958147 | 0.84 | HTT (0.44) | MAPTCYP3A4ALDH1A1MEN1LMNA | |
| SCHEMBL4746323 | 0.81 | HDAC1 (0.40) | — | |
| SCHEMBL28131741 | 0.77 | MAPT (0.53) | MAPTALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL23236146 | 0.73 | DPP4 (0.44) | MAPTALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL1271748 | 0.71 | PDK1 (0.44) | MAPTCYP3A4ALDH1A1MEN1LMNA | |
| SCHEMBL4749634 | 0.70 | GRK6 (0.42) | MAPTCYP3A4TSHRKAT2BALDH1A1 | |
| SCHEMBL11909744 | 0.70 | KAT2B (0.45) | MAPTCYP3A4KAT2BALDH1A1MEN1 | |
| SCHEMBL11909741 | 0.70 | KAT2B (0.45) | MAPTCYP3A4KAT2BALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008119718-A1 | COMPOUNDS WHICH HAVE ACTIVITY AT M1 RECEPTOR AND THEIR USES IN MEDICINE | GLAXO GROUP LIMITED (GB) | 2008-10-09 | — | — | WO | disclosed |