Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 2/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.54 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.54 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.54 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.54 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.54 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.54 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.54 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4750144 | 0.85 | LDLR (0.47) | HDAC3HDAC1HDAC2ROCK2KMT2A | |
| SCHEMBL9335546 | 0.78 | KMT2A (0.53) | HDAC3HDAC1HDAC2ROCK2KMT2A | |
| SCHEMBL6508976 | 0.77 | KMT2A (0.67) | ROCK2KMT2AALDH1A1MEN1CYP1A2 | |
| SCHEMBL10198173 | 0.76 | ROCK2 (0.61) | ROCK2KMT2AALDH1A1MEN1CYP1A2 | |
| SCHEMBL13363465 | 0.74 | HDAC1 (0.91) | HDAC3HDAC1HDAC2HDAC4HDAC7 | |
| SCHEMBL11597168 | 0.73 | HDAC3 (0.72) | HDAC3HDAC1HDAC2HDAC4HDAC7 | |
| SCHEMBL11418046 | 0.73 | HDAC3 (0.68) | HDAC3HDAC1HDAC2HDAC4HDAC7 | |
| SCHEMBL629093 | 0.73 | HDAC3 (0.68) | HDAC3HDAC1HDAC2HDAC4HDAC7 | |
| SCHEMBL7935572 | 0.73 | DDX3X (0.65) | HDAC3HDAC1HDAC2HDAC4HDAC7 | |
| SCHEMBL29850847 | 0.72 | EPHX2 (0.63) | KMT2ASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008122667-A2 | UREYLENE DERIVATIVES | SCHOOL OF PHARMACY (GB) | 2008-10-16 | — | — | WO | disclosed |