Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 9/20 | 0.64 |
| ▸ | BRAF | P15056 | 9/20 | 0.61 |
| ▸ | CSF1R | P07333 | 3/20 | 0.56 |
| ▸ | KIT | P10721 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4788992 | 0.94 | LCK (0.65) | LCKBRAFCSF1RKIT | |
| SCHEMBL4750073 | 0.93 | BRAF (0.64) | LCKBRAFCSF1RKIT | |
| SCHEMBL14042457 | 0.90 | BRAF (0.61) | LCKBRAFCSF1RKIT | |
| SCHEMBL14042250 | 0.89 | BRAF (0.59) | LCKBRAFCSF1RKIT | |
| SCHEMBL14042437 | 0.88 | BRAF (0.67) | LCKBRAFCSF1RKIT | |
| SCHEMBL14042258 | 0.88 | BRAF (0.58) | LCKBRAFCSF1RKIT | |
| SCHEMBL4862030 | 0.88 | LCK (0.64) | LCKBRAFCSF1RKIT | |
| SCHEMBL14042704 | 0.88 | BRAF (0.64) | LCKBRAFCSF1RKIT | |
| SCHEMBL14042465 | 0.88 | BRAF (0.57) | LCKBRAFCSF1RKIT | |
| SCHEMBL14042245 | 0.88 | BRAF (0.57) | BRAFCSF1RKIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008124393-A1 | BENZOTHIAZOLE DERIVATIVES AND THEIR USE AS PROTEIN KINASE INHIBITORS | IRM LLC (BM) | 2008-10-16 | — | — | WO | disclosed |
| WO-2008124393-A1 | BENZOTHIAZOLE DERIVATIVES AND THEIR USE AS PROTEIN KINASE INHIBITORS | IRM LLC (BM) | 2008-10-16 | — | — | WO | disclosed |