Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 4/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 6/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8151416 | 1.00 | ALDH1A1 (0.44) | ALDH1A1MAP4K4LMNAHDAC4P2RX7 | |
| SCHEMBL17115021 | 0.88 | HSD11B1 (0.45) | ALDH1A1LMNAHDAC4HSD11B1DRD2 | |
| SCHEMBL23578120 | 0.85 | HSD11B1 (0.47) | ALDH1A1MAP4K4LMNAHDAC4HSD11B1 | |
| SCHEMBL8159437 | 0.85 | HSD11B1 (0.47) | ALDH1A1MAP4K4LMNAHDAC4HSD11B1 | |
| SCHEMBL881576 | 0.81 | MAP4K4 (0.37) | MAP4K4P2RX7ALOX5 | |
| SCHEMBL2701341 | 0.80 | ALDH1A1 (0.54) | ALDH1A1MAP4K4LMNAHDAC4P2RX7 | |
| SCHEMBL8142155 | 0.77 | ALDH1A1 (0.42) | ALDH1A1MAP4K4LMNAHDAC4P2RX7 | |
| SCHEMBL10240705 | 0.76 | MAP4K4 (0.45) | MAP4K4ALOX5 | |
| SCHEMBL1625869 | 0.75 | MAP4K4 (0.61) | ALDH1A1MAP4K4LMNAHDAC4P2RX7 | |
| SCHEMBL15349038 | 0.74 | ALDH1A1 (0.48) | ALDH1A1MAP4K4LMNAHDAC4P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008117148-A1 | SUBSTITUTED OXADIAZOLE ANALOGS AS CALCIUM CHANNEL ANTAGONISTS | PFIZER PRODUCTS INC. (US) | 2008-10-02 | — | — | WO | disclosed |