Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | SLC10A2 | Q12908 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.42 |
| ▸ | MET | P08581 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TDP2 | O95551 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4747315 | 0.90 | EGFR (0.49) | EGFRMCHR1METMAPTGAA | |
| SCHEMBL4750651 | 0.89 | ALDH1A1 (0.43) | EGFRMCHR1MAPTGAATHRB | |
| SCHEMBL4750620 | 0.88 | RAD51 (0.40) | EGFRMETRAB9AMEN1KMT2A | |
| SCHEMBL4750005 | 0.83 | RAD51 (0.39) | EGFRMAPTKDM4ERAB9ARXFP1 | |
| SCHEMBL4747281 | 0.83 | EGFR (0.46) | EGFRMCHR1METMAPTGAA | |
| SCHEMBL5816238 | 0.82 | ALDH1A1 (0.40) | MAPTGAATHRBKDM4EMAPK1 | |
| SCHEMBL4750212 | 0.81 | PSD (0.42) | EGFRMAPTRAB9AMEN1KMT2A | |
| SCHEMBL4750210 | 0.80 | EGFR (0.39) | EGFRMETRAB9AMAPK1RXFP1 | |
| SCHEMBL4747830 | 0.75 | RAD51 (0.42) | MAPTKDM4ERAB9AMAPK1NPC1 | |
| SCHEMBL4747889 | 0.75 | ALDH1A1 (0.40) | EGFRMAPTGAATHRBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008123755-A1 | A PHARMACEUTICAL COMPOSITIONS CONTAINING LACTAM TYPE PYRIDINE DERIVATIVES AS AN EFFECTIVE INGREDIENT FOR THE PREVENTION AND TREATMENT OF ISCHEMIA | SK CHEMICALS CO., LTD. (KR) | 2008-10-16 | — | — | WO | claimed |
| WO-2006112666-A1 | PYRIDINE DERIVATIVES, METHODS OF THEIR PREPARATIONS, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | SK CHEMICALS CO., LTD. (KR) | 2006-10-26 | — | — | WO | disclosed |