Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | CLK1 | P49759 | 1/20 | 0.37 |
| ▸ | EDNRA | P25101 | 1/20 | 0.37 |
| ▸ | FPR1 | P21462 | 1/20 | 0.37 |
| ▸ | FPR2 | P25090 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | PTGES | O14684 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8103222 | 0.87 | KDM1A (0.41) | MAPTKIF11 | |
| SCHEMBL4744284 | 0.71 | KMT2A (0.47) | ALDH1A1MAPTLMNATP53MAOB | |
| SCHEMBL9201878 | 0.66 | HDAC3 (0.41) | ALDH1A1LMNAKIF11SMN1; SMN2 | |
| SCHEMBL16108162 | 0.65 | SMN1; SMN2 (0.50) | MAPTLMNATP53NPBWR1SMN1; SMN2 | |
| SCHEMBL29782607 | 0.63 | L3MBTL1 (0.58) | ALDH1A1MAPTLMNAMAOBGAA | |
| SCHEMBL167016 | 0.63 | L3MBTL1 (0.58) | ALDH1A1MAPTLMNAMAOBGAA | |
| SCHEMBL8105812 | 0.63 | KDM1A (0.40) | MAPTLMNA | |
| SCHEMBL13247934 | 0.63 | NR1H4 (0.63) | ALDH1A1MAPTTP53KIF11MAOB | |
| SCHEMBL11812241 | 0.62 | SLC6A4 (0.47) | KIF11 | |
| SCHEMBL27295380 | 0.61 | MAPT (0.57) | ALDH1A1MAPTLMNAGAATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008112674-A1 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | IRM LLC (BM) | 2008-09-18 | — | — | WO | disclosed |