Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 4/20 | 0.36 |
| ▸ | MAOA | P21397 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 2/20 | 0.35 |
| ▸ | MMP14 | P50281 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | NAAA | Q02083 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4808531 | 0.85 | ATM (0.41) | KMT2AMAPK1ADAMTS5MAOBMAOA | |
| SCHEMBL4806238 | 0.79 | NTRK1 (0.39) | KMT2AMAPK1ADAMTS5MEN1HTT | |
| SCHEMBL8103222 | 0.68 | KDM1A (0.41) | KMT2AMEN1MAPT | |
| SCHEMBL29349910 | 0.64 | MAOA (0.52) | KMT2AMAOBMAOALMNAMEN1 | |
| SCHEMBL3716891 | 0.64 | MAOA (0.52) | KMT2AMAOBMAOALMNAMEN1 | |
| SCHEMBL11833712 | 0.62 | MMP13 (0.42) | KMT2AADAMTS5MEN1MMP13MMP14 | |
| SCHEMBL6686421 | 0.61 | GFER (0.47) | ADAMTS5MAOBMAOAHPGDMMP13 | |
| SCHEMBL10715309 | 0.60 | MAPT (0.54) | KMT2AMAOBMEN1MMP13ALDH1A1 | |
| SCHEMBL16890736 | 0.60 | ALDH1A1 (0.60) | KMT2AMAOBMAOALMNAMEN1 | |
| SCHEMBL4436971 | 0.60 | CNR1 (0.46) | KMT2ALMNAMEN1POLBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008112674-A1 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | IRM LLC (BM) | 2008-09-18 | — | — | WO | disclosed |