Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL248011 | 0.89 | THRB (0.43) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL56973 | 0.89 | THRB (0.43) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL150780 | 0.83 | THRB (0.48) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL486580 | 0.82 | APEX1 (0.41) | TSHRTHRBALDH1A1POLBAPEX1 | |
| 1,3-Butanediol SCHEMBL1172320 | 0.81 | TSHR (0.38) | TSHRTHRBALDH1A1APEX1HTT | |
| SCHEMBL23004645 | 0.80 | TSHR (0.43) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL17703263 | 0.80 | TSHR (0.43) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL4450451 | 0.80 | TSHR (0.58) | TSHRTHRBALDH1A1POLBAPEX1 | |
| Ethylene Glycol SCHEMBL28321709 | 0.78 | TSHR (0.64) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL21657670 | 0.77 | THRB (0.43) | TSHRTHRBALDH1A1POLBAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2412738-A1 | TRANSPARENT COMPOSITE MATERIAL | SHOWA DENKO K.K. (JP) | 2012-02-01 | — | — | EP | disclosed |