Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.53 |
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.52 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.52 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL446475 | 0.81 | TDP1 (0.55) | TDP1ALDH1A1GPR35TSHRMAPK1 | |
| SCHEMBL8147133 | 0.81 | ALDH1A1 (0.58) | TDP1ALDH1A1GPR35TSHRMAPK1 | |
| SCHEMBL11300569 | 0.81 | HSD17B10 (0.62) | TDP1ALDH1A1TSHRMAPK1HIF1A | |
| SCHEMBL11865353 | 0.80 | TDP1 (0.46) | TDP1ALDH1A1GPR35TSHRMAPK1 | |
| SCHEMBL11856556 | 0.79 | ALDH1A1 (0.47) | TDP1ALDH1A1GPR35TSHRMAPK1 | |
| SCHEMBL11451357 | 0.78 | HSD17B10 (0.44) | TDP1ALDH1A1GPR35TSHRMAPK1 | |
| SCHEMBL17704246 | 0.78 | TDP1 (0.52) | TDP1ALDH1A1GPR35TSHRMAPK1 | |
| SCHEMBL3656487 | 0.78 | TDP1 (0.52) | TDP1ALDH1A1GPR35TSHRMAPK1 | |
| SCHEMBL7945433 | 0.77 | HSD17B10 (0.62) | TDP1ALDH1A1TSHRMAPK1TP53 | |
| SCHEMBL28840504 | 0.77 | ALDH1A1 (0.56) | TDP1ALDH1A1TSHRMAPK1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008118784-A1 | GLYCOPEPTIDE AND LIPOGLYCOPEPTIDE ANTIBIOTICS WITH IMPROVED SOLUBILITY | TARGANTA THERAPEUTICS CORP. (US) | 2008-10-02 | — | — | WO | disclosed |