Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 5/20 | 0.44 |
| ▸ | DRD4 | P21917 | 5/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | FPR3 | P25089 | 1/20 | 0.42 |
| ▸ | FPR2 | P25090 | 1/20 | 0.42 |
| ▸ | NOS3 | P29474 | 1/20 | 0.41 |
| ▸ | NOS1 | P29475 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4745396 | 0.86 | HRH3 (0.46) | DRD2DRD4HRH3ALDH1A1DRD3 | |
| SCHEMBL4743111 | 0.82 | HRH3 (0.56) | HRH3 | |
| SCHEMBL4743288 | 0.82 | HRH3 (0.56) | HRH3 | |
| SCHEMBL4743293 | 0.81 | MEN1 (0.56) | DRD2HRH3ALDH1A1 | |
| SCHEMBL4747505 | 0.80 | MAPT (0.42) | DRD2DRD4NOS3NOS1HRH3 | |
| SCHEMBL4743100 | 0.79 | PSEN1 (0.41) | DRD2DRD4NOS3NOS1HRH3 | |
| SCHEMBL4744714 | 0.79 | AVPR1B (0.46) | HRH3AVPR1BSMN1; SMN2 | |
| SCHEMBL4746674 | 0.78 | AVPR1B (0.46) | HRH3AVPR1B | |
| SCHEMBL4745334 | 0.77 | HRH3 (0.47) | HRH3AVPR1B | |
| SCHEMBL12332380 | 0.77 | CHRM2 (0.66) | DRD2DRD4CHRM2FPR3FPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008107320-A1 | PIPERIDINE AND PIPERAZINE DERIVATIVES USED AS ANTI-NEOPLASIC AGENTS OR CELL PROLIFERATION INHIBITORS | CEREP (FR) | 2008-09-12 | — | — | WO | claimed |