Ether

Ether

SCHEMBL474769

CCOCC.CCc1ccc(-c2ccccc2)c(CC)c1CC

nearest known ligand 0.35

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA3 P0DMS8 4/20 0.35
USP7 Q93009 2/20 0.33
LMNA P02545 1/20 0.33
GCGR P47871 1/20 0.33
BACE1 P56817 1/20 0.33
PDCD1 Q15116 1/20 0.33
CD274 Q9NZQ7 1/20 0.33
DPP4 P27487 1/20 0.32
PLA2G2A P14555 1/20 0.32
L3MBTL1 Q9Y468 3/20 0.32
ALDH1A1 P00352 2/20 0.32
HPGD P15428 2/20 0.32
KDM4E B2RXH2 1/20 0.32
MEN1 O00255 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP3A4 P08684 1/20 0.32
GAA P10253 1/20 0.32
CYP2D6 P10635 1/20 0.32
CYP2C9 P11712 1/20 0.32
CYP2C19 P33261 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL473259 0.91 DPP4 (0.38) USP7GCGRBACE1PDCD1CD274
Water SCHEMBL474768 0.89 DPP4 (0.37) USP7GCGRPDCD1CD274DPP4
Aziridine SCHEMBL11855718 0.83 HTR6 (0.38) CYP2D6
SCHEMBL9182911 0.79 TP53 (0.39) LMNAALDH1A1KDM4EMEN1GAA
SCHEMBL21753489 0.79 DPP4 (0.34) USP7GCGRPDCD1CD274DPP4
Ether SCHEMBL9719794 0.78 DPP4 (0.50) LMNAPDCD1CD274DPP4L3MBTL1
SCHEMBL29101386 0.78 PTGS1 (0.46) LMNAGCGRL3MBTL1ALDH1A1HPGD
SCHEMBL996207 0.78 USP7 (0.33) ADORA3USP7GCGRPLA2G2A
SCHEMBL9185899 0.77 TP53 (0.40)
SCHEMBL8679020 0.77 CD274 (0.47) ADORA3USP7GCGRPDCD1CD274

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2412703-B1 URETHANE COMPOUND AND PROCESS FOR PRODUCTION THEREOF, AND ISOCYANATE AND PROCESS FOR PRODUCTION THEREOF MITSUI CHEMICALS INC (JP) 2016-06-29 EP disclosed
EP-2412703-A1 URETHANE COMPOUND AND PROCESS FOR PRODUCTION THEREOF, AND ISOCYANATE AND PROCESS FOR PRODUCTION THEREOF Mitsui Chemicals, Inc. (JP) 2012-02-01 EP disclosed