SCHEMBL4747690

SCHEMBL4747690

O=S(=O)(O)O[C@@H]1[C@@H](OS(=O)(=O)O)[C@H](O)[C@@H](CO)O[C@@H]1O

nearest known ligand 0.41

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
LGALS3 P17931 1/20 0.39
SLC2A1 P11166 1/20 0.38
MAPK1 P28482 1/20 0.37
CA12 O43570 4/20 0.37
CA2 P00918 4/20 0.37
CA9 Q16790 4/20 0.37
CA1 P00915 3/20 0.37
MAPT P10636 1/20 0.36
LGALS8 O00214 2/20 0.35
BLM P54132 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8201748 1.00 LGALS3 (0.39) LGALS3SLC2A1MAPK1CA12CA2
SCHEMBL1116558 1.00 LGALS3 (0.39) LGALS3SLC2A1MAPK1CA12CA2
SCHEMBL1116562 1.00 LGALS3 (0.39) LGALS3SLC2A1MAPK1CA12CA2
SCHEMBL741519 0.91 SLC2A1 (0.42) LGALS3SLC2A1MAPK1CA12CA2
SCHEMBL150778 0.91 SLC2A1 (0.42) LGALS3SLC2A1MAPK1CA12CA2
SCHEMBL5318200 0.91 SLC2A1 (0.42) LGALS3SLC2A1MAPK1CA12CA2
SCHEMBL3653142 0.89 CA2 (0.40) LGALS3SLC2A1MAPK1CA12CA2
SCHEMBL7049511 0.89 CA2 (0.40) LGALS3SLC2A1MAPK1CA12CA2
SCHEMBL1116556 0.89 CA2 (0.40) LGALS3SLC2A1MAPK1CA12CA2
SCHEMBL22121795 0.89 CA2 (0.40) LGALS3SLC2A1MAPK1CA12CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3681504-B1 METHODS OF DETECTION USING X-RAY FLUORESCENCE ICAGEN INC (US) 2023-08-23 EP disclosed
US-11573224-B2 Methods of detection using X-ray fluorescence ICAGEN, LLC (US) 2023-02-07 US disclosed
US-11446398-B2 Regulated biocircuit systems OBSIDIAN THERAPEUTICS, INC. (US) 2022-09-20 US disclosed
US-20210254056-A1 IDENTIFICATION AND TARGETED MODULATION OF GENE SIGNALING NETWORKS CAMP4 THERAPEUTICS CORPORATION 2021-08-19 US disclosed
US-10877035-B2 Advanced drug development and manufacturing ICAGEN, LLC (US) 2020-12-29 US disclosed
US-20200278346-A1 METHODS OF DETECTION USING X-RAY FLUORESCENCE ADJACENT ACQUISITION CO., LLC 2020-09-03 US disclosed
EP-3681504-A1 METHODS OF DETECTION USING X-RAY FLUORESCENCE Icagen, Inc. (US) 2020-07-22 EP disclosed
US-20190192691-A1 REGULATED BIOCIRCUIT SYSTEMS OBSIDIAN THERAPEUTICS, INC. 2019-06-27 US disclosed
WO-2019055754-A1 METHODS OF DETECTION USING X-RAY FLUORESCENCE ICAGEN, INC. (US) 2019-03-21 WO disclosed
US-20150309021-A1 Advanced Drug Development and Manufacturing LOS ALAMOS NATIONAL SECURITY, LLC 2015-10-29 US disclosed
EP-2511844-B1 X-ray microscope XRPRO SCIENCES INC (US) 2015-08-12 EP disclosed
EP-2511844-A2 Advanced drug development and manufacturing Los Alamos National Security, LLC (US) 2012-10-17 EP disclosed
EP-2084519-B1 X-RAY FLUORESCENCE ANALYSIS METHOD LOS ALAMOS NAT SECURITY LLC (US) 2012-08-01 EP disclosed
WO-2008124930-A1 USE OF CYCLOHEXANEHEXOL DERIVATIVES FOR THE TREATMENT OF POLYGLUTAMINE DISEASES MCLAURIN JOANNE (CA) 2008-10-23 WO disclosed
US-20080220441-A1 Advanced drug development and manufacturing THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2008-09-11 US disclosed