Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LGALS3 | P17931 | 1/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 4/20 | 0.37 |
| ▸ | CA2 | P00918 | 4/20 | 0.37 |
| ▸ | CA9 | Q16790 | 4/20 | 0.37 |
| ▸ | CA1 | P00915 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | LGALS8 | O00214 | 2/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4747690 | 1.00 | LGALS3 (0.39) | LGALS3SLC2A1MAPK1CA12CA2 | |
| SCHEMBL1116558 | 1.00 | LGALS3 (0.39) | LGALS3SLC2A1MAPK1CA12CA2 | |
| SCHEMBL1116562 | 1.00 | LGALS3 (0.39) | LGALS3SLC2A1MAPK1CA12CA2 | |
| SCHEMBL741519 | 0.91 | SLC2A1 (0.42) | LGALS3SLC2A1MAPK1CA12CA2 | |
| SCHEMBL150778 | 0.91 | SLC2A1 (0.42) | LGALS3SLC2A1MAPK1CA12CA2 | |
| SCHEMBL5318200 | 0.91 | SLC2A1 (0.42) | LGALS3SLC2A1MAPK1CA12CA2 | |
| SCHEMBL3653142 | 0.89 | CA2 (0.40) | LGALS3SLC2A1MAPK1CA12CA2 | |
| SCHEMBL7049511 | 0.89 | CA2 (0.40) | LGALS3SLC2A1MAPK1CA12CA2 | |
| SCHEMBL1116556 | 0.89 | CA2 (0.40) | LGALS3SLC2A1MAPK1CA12CA2 | |
| SCHEMBL22121795 | 0.89 | CA2 (0.40) | LGALS3SLC2A1MAPK1CA12CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1054664-A1 | METHOD FOR MODULATING MACROPHAGE ACTIVATION | Neurochem, Inc. (CA) | 2000-11-29 | — | — | EP | disclosed |
| WO-1999040909-A1 | METHOD FOR MODULATING MACROPHAGE ACTIVATION | NEUROCHEM, INC. (CA) | 1999-08-19 | — | — | WO | disclosed |